Results 181 to 190 of about 655,970 (311)

What are transgenic mice and how will they affect medicine?

, 1986
Milton M. Weiser
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Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice. [PDF]

, 1994
Bart J. van Vlijmen, Arn M. J. M. van den Maagdenberg, Marion J. Gijbels, Hans van der Boom, Harm HogenEsch, Rune R. Frants, Marten H. Hofker, Louis M. Havekes   +7 more
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Advances in CRISPR‐Cas9 in lineage tracing of model animals

Animal Models and Experimental Medicine, EarlyView.
Cell lineage tracing is a key technology for describing the developmental history of individual progenitor cells and assembling them to form a lineage development tree. However, traditional methods have limitations of poor stability and insufficient resolution.
Jingchao Cao, Zihang Guo, Xueling Xu, Pan Li, Yi Fang, Shoulong Deng   +5 more
wiley   +1 more source

Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. Dependence on natural flanking sequences. [PDF]

, 1992
Xian‐Cheng Jiang, Luis B. Agellon, A Walsh, J L Breslow, Alan R. Tall   +4 more
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Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

Animal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng   +5 more
wiley   +1 more source

Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice-An unbiased functional study. [PDF]

Proc Natl Acad Sci U S A
Yoon H, Gerdes LA, Beigel F, Sun Y, Kövilein J, Wang J, Kuhlmann T, Flierl-Hecht A, Haller D, Hohlfeld R, Baranzini SE, Wekerle H, Peters A.   +12 more
europepmc   +1 more source

Intestinal expression of the human apoA-I gene in transgenic mice is controlled by a DNA region 3' to the gene in the promoter of the adjacent convergently transcribed apoC-III gene.

, 1993
A Walsh, Neal Azrolan, K. Wang, A Marcigliano, Anita M. O'Connell, Jan L. Breslow   +5 more
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HCN2‐Associated Neurodevelopmental Disorders: Data from Patients and Xenopus Cell Models

Annals of Neurology, EarlyView.
Objective We aimed to characterize the phenotypic spectrum and functional consequences associated with variants in HCN2, encoding for the hyperpolarization‐activated cyclic nucleotide (HCN) gated channel 2. Methods GeneMatcher facilitated the recruitment of 21 individuals with HCN2 variants from 15 unrelated families, carrying HCN2 variants.
Clara Houdayer, A. Marie Phillips, Marie Chabbert, Jennifer Bourreau, Reza Maroofian, Henry Houlden, Kay Richards, Nebal Waill Saadi, Eliška Dad'ová, Patrick Van Bogaert, Mailys Rupin, Boris Keren, Perrine Charles, Thomas Smol, Audrey Riquet, Lynn Pais, Anne O'Donnell‐Luria, Grace E. VanNoy, Allan Bayat, Rikke S Møller, Kern Olofsson, Rami Abou Jamra, Steffen Syrbe, Majed Dasouki, Laurie H. Seaver, Jennifer A. Sullivan, Vandana Shashi, Fowzan S. Alkuraya, Alexis F. Poss, J. Edward Spence, Rhonda E. Schnur, Ian C. Forster, Chaseley E. Mckenzie, Cas Simons, Min Wang, Penny Snell, Kavitha Kothur, Michael Buckley, Tony Roscioli, Noha Elserafy, Benjamin Dauriat, Vincent Procaccio, Daniel Henrion, Guy Lenaers, Estelle Colin, Nienke E. Verbeek, Koen L. Van Gassen, Claire Legendre, Dominique Bonneau, Christopher A. Reid, Katherine B. Howell, Alban Ziegler, Christian Legros   +52 more
wiley   +1 more source

Neuroprotective role of sialic-acid-binding immunoglobulin-like lectin-11 in humanized transgenic mice. [PDF]

Front Neurosci
Abou Assale T, Afrang N, Wissfeld J, Cuevas-Rios G, Klaus C, Linnartz-Gerlach B, Neumann H.   +6 more
europepmc   +1 more source

Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter. [PDF]

, 1992
Muayyad R. Al‐Ubaidi, R. L. Font, Alexander B. Quiambao, MARY J. KEENER, G. I. Liou, Paul A. Overbeek, Wolfgang Baehr   +6 more
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