Results 181 to 190 of about 3,709,047 (395)
Small Ubiquitin-Like Modifier 3–Modified Proteome Regulated by Brain Ischemia in Novel Small Ubiquitin-Like Modifier Transgenic Mice [PDF]
, 2014 Wei Yang +8 more
openalex +1 more source
Advanced Science, EarlyView.This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu +11 more
wiley +1 more source
TMEM206 gene knockout improves balance performance in SCA1 transgenic mice. [PDF]
IBRO Neurosci RepZhang JH, Qin Y, Sun SC.
europepmc +1 more source
Oral delivery of transgenic plant-derived HIV-1 p24 antigen in low doses shows a superior priming effect in mice compared to higher doses [PDF]
, 2012 Ingrid Lindh +5 more
openalex +1 more source
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
Nature, 1988 P. Kisielow +4 more
semanticscholar +1 more source
Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition
Advanced Science, EarlyView.Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han +9 more
wiley +1 more source
Viral oncogenes drive biphenotypic lymphoproliferative malignancy in transgenic mice. [PDF]
Sci RepRauch DA, Harding J, Joseph A, Ratner L.
europepmc +1 more source
Targeted expression of a toxin gene to adipose tissue: transgenic mice resistant to obesity. [PDF]
, 1993 Susan R. Ross +2 more
openalex +1 more source