Results 181 to 190 of about 1,952,729 (355)

Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids

open access: yesAdvanced Science, EarlyView.
To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun   +9 more
wiley   +1 more source

Autonomous bioluminescence emission from transgenic mice. [PDF]

open access: yesSci Adv
Kiszka KA   +6 more
europepmc   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

open access: yesAdvanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan   +19 more
wiley   +1 more source

Establishment an echovirus 6 infection model based on hFcRn transgenic mice. [PDF]

open access: yesFront Med (Lausanne)
Li F   +7 more
europepmc   +1 more source

Effects of Individualized Treadmill Endurance Training on Oxidative Stress in Skeletal Muscles of Transgenic Sickle Mice [PDF]

open access: hybrid, 2019
Étienne Gouraud   +12 more
openalex   +1 more source

Additional file 1 of Screening UFMylation-associated genes in heart tissues of Ufm1-transgenic mice

open access: gold, 2023
Jiajia Hu   +5 more
openalex   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

open access: yesAdvanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng   +7 more
wiley   +1 more source

Retraction: Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease. [PDF]

open access: yesOncotarget
Braidy N   +9 more
europepmc   +1 more source

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