Results 41 to 50 of about 605,111 (136)

Retinal degeneration is rescued in transgenic rd mice by expression of the cGMP phosphodiesterase ß subunit [PDF]

, 1992
The ß subunit of the cGMP phosphodiesterase (PDE) gene has been identified as the candidate gene for retinal degeneration in the rd mouse. To study the molecular mechanisms underlying degeneration and the potential for gene repair, we have expressed a ...
Applebury, Meredithe L., Farber, Debora B., Flannery, John G., Lem, Janis, Li, Tiansen, Simon, Melvin I.   +5 more
core  

PRODUCTION OF HIGH LEVELS OF TRANSGENC FACTOR IX WITHOUT GENE RESCUE, AND ITS THERAPEUTIC USES [PDF]

, 2011
A non-human transgenic mammalian animal, as described above, contains an exogenous double stranded DNA sequence stably integrated into the genome of the animal, which comprises cis-acting regulatory units operably linked to a DNA sequence encoding human ...
Cooper, Julian D., O\u27Sickey, Tanya K., Velander, William Hugold   +2 more
core   +1 more source

Overexpression of alpha(1)-acid glycoprotein in transgenic mice leads to sensitisation to acute colitis. [PDF]

, 2002
BAUMANN, H, BERGER, FG, Brouckaert, Peter, Hochepied, Tino, Libert, Claude, Steidler, Lothar, Wullaert, Andy   +6 more
core   +2 more sources

Exploring the Chemopreventive and Antioxidant Effects of Spearmint Leaf Hydroethanolic Extract in HPV16-transgenic Mice. [PDF]

In Vivo
Jesus TM, Azevedo T, Silva-Reis R, Ferreira T, Nascimento-Gonçalves E, Medeiros C, Ferreira J, Gama A, Gaivão I, Pires MJ, Lanzarin G, Félix L, Venâncio C, Medeiros R, Bastos MMSM, Finimundy TC, Barros L, Gil DA Costa RM, Oliveira PA.   +18 more
europepmc   +1 more source

MAIT cell deficiency exacerbates neuroinflammation in P301S human tau transgenic mice. [PDF]

J Neuroinflammation
Zhang Y, Yang Z, Jiang N, Tan X, Jiang P, Cao G, Yang Q.   +6 more
europepmc   +1 more source

Application of Humanized MHC Transgenic Mice in the Screening of HLA-Restricted T Cell Epitopes for Influenza Vaccines. [PDF]

Vaccines (Basel)
Wei Y, Sun K, Han X, Sun Y, Zhang J, Wang Y, Yin Q, Yang T, Yuan K, Li M, Zhao G.   +10 more
europepmc   +1 more source

Application of transgenic mice to the molecular pathogenesis of cataract. [PDF]

Int J Ophthalmol
Zhang Y, Chen XY, Hu YZ, Zhang X, Zheng SF, Hu SS.   +5 more
europepmc   +1 more source

Correction: Urolithin a Improves Motor Dysfunction Induced by Copper Exposure in SOD1^G93A Transgenic Mice Via Activation of Mitophagy. [PDF]

Mol Neurobiol
Zhang H, Gao C, Yang D, Nie L, He K, Chen C, Li S, Huang G, Zhou L, Huang X, Wu D, Liu J, Huang Z, Wang J, Li W, Zhang Z, Yang X, Zou L.   +17 more
europepmc   +1 more source

Prediction of human pharmacokinetics of Fc-engineered therapeutic monoclonal antibodies using human FcRn transgenic mice. [PDF]

MAbs
Haraya K, Ichikawa T, Murao N, Katada H, Kuramochi T.   +4 more
europepmc   +1 more source

Target Validation Studies of PS48, a PDK-1 Allosteric Agonist, for the Treatment of Alzheimer's Disease Phenotype in APP/PS1 Transgenic Mice. [PDF]

Int J Mol Sci
Querfurth HW, Lemere C, Ciola J, Havas D, Xia W, Lee HK.   +5 more
europepmc   +1 more source