Results 201 to 210 of about 1,635,517 (312)

Additional file 3: Figure S3. of N-truncated Aβ4–x peptides in sporadic Alzheimer’s disease cases and transgenic Alzheimer mouse models

, 2017
Oliver Wirths, Susanne Walter, Inga Kraus, Hans‐Wolfgang Klafki, Martina Stazi, Timo Oberstein, Jorge Ghiso, Jens Wiltfang, Thomas Bayer, Sascha Weggen   +9 more
openalex   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

Transgenic mouse models of sodium and potassium channelopathies in epilepsy: insights into disease mechanisms and therapeutics. [PDF]

Biosci Rep
Hammer MF.
europepmc   +1 more source

Illuminating the Intracellular World: Breakthroughs in Nanoscale Optoelectronics

Advanced Electronic Materials, EarlyView.
This perspective explores optoelectronic biointerfaces spanning macroscale flexible devices to nanoscale intracellular systems, emphasizing their integration across dimensions. It examines capacitive, Faradaic, and photothermal mechanisms that enable light‐driven control of cellular activity and highlights key material and design challenges in ...
Tania Assaf, Menahem Y. Rotenberg
wiley   +1 more source

<i>In vivo</i> 3D imaging of ovarian cancer outgrowth in transgenic mouse model with optical coherence tomography. [PDF]

J Biomed Opt
Han H, Mukhamedjanova A, Connolly DC, Iwanicki MP, Wang S.   +4 more
europepmc   +1 more source

Renal HIV Expression Is Unaffected by Serum LPS Levels in an HIV Transgenic Mouse Model of LPS Induced Kidney Injury

, 2011
Jeremy S. Leventhal, Zygimantas C. Alsauskas, Alexandra Snyder, Pengfei Gong, Bin Wang, Vivette D. D’Agati, Michael J. Ross   +6 more
openalex   +2 more sources

Reduced CB1 Cannabinoid Receptor Expression in Alzheimer's Disease and Transgenic Mouse Models

AGING MEDICINE, EarlyView.
CB1 receptor (CB1R) expression was significantly reduced in the hippocampus, medial frontal gyrus, and superior temporal gyrus of Alzheimer's patients. CB1R levels negatively correlated with amyloid‐β and tau pathology. In addition, CB1R expression was also reduced in the cortex of 5xFAD mice and in the hippocampus of Tg4‐42 mice.
Nike von Borcke, Amrei Vivian Purwien, Annik Steiert, Henrike Hasecke, Yvonne Bouter   +4 more
wiley   +1 more source

Modeling tumor relapse using proliferation tracing and ablation transgenic mouse. [PDF]

NPJ Breast Cancer
Zhao C, Zheng XN, Huang HY, Tian L.
europepmc   +1 more source

Immunoprotectivity of HLA-A2 CTL Peptides Derived from Respiratory Syncytial Virus Fusion Protein in HLA-A2 Transgenic Mouse

, 2011
Hsiao-Yun Shao, Yi‐Wen Lin, Shu‐Ling Yu, Hsiang‐Yin Lin, Ebenezer Chitra, Yung‐Chen Chang, Charles Sia, Pele Chong, Ming-Tao Hsu, Olivia L. Wei, Yen‐Hung Chow   +10 more
openalex   +2 more sources

Advances in Gastric Cancer Research: Insights Into Carcinogenesis, the Tumor Microenvironment, Metastasis, and Factors Influencing Prognosis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba, Takatsugu Ishimoto, Yoshifumi Baba, Hiromitsu Hayashi, Masaaki Iwatsuki   +4 more
wiley   +1 more source