Results 31 to 40 of about 2,621,599 (302)
Biomedicines, 2022 Colorectal cancer (CRC) is a malignant disease that is the second most common cancer worldwide. CRC arises from the complex interactions among a variety of genetic and environmental factors. To understand the mechanism of colon tumorigenesis, preclinical
Chuangen Li +3 more
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Enhanced characterization of beta cell mass in a Tg(Pdx1-GFP) mouse model [PDF]
BioImpacts, 2022 Introduction: Measurement of pancreatic beta cell mass in animal models is a common assay in diabetes researches. Novel whole-organ clearance methods in conjunction with transgenic mouse models hold tremendous promise to improve beta cell mass ...
Fatemeh Karami +8 more
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9th transgenic technology meeting (TT2010) in Berlin, Germany: a meeting report
, 2010 The first Transgenic Technology (TT) Meeting was organized in 1999 by Johannes Wilbertz, Karolinska Institute, Stockholm, Sweden as a regional meeting.
Saunders, T, Sobieszczuk, Peter
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Transmissibility of caprine scrapie in ovine transgenic mice
BMC Veterinary Research, 2012 Background The United States control program for classical ovine scrapie is based in part on the finding that infection is typically spread through exposure to shed placentas from infected ewes. Transmission from goats to sheep is less well described.
O’Rourke Katherine I +6 more
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Islet Dysfunction in a Novel Transgenic Model of T Cell Insulitis
Biomolecules, 2021 The newly established CD3FLAG-mIR transgenic mouse model on a C57Bl/6 background has a FLAG tag on the mouse Insulin Receptor (mIR), specifically on T cells, as the FLAG-tagged mIR gene was engineered behind CD3 promoter and enhancer.
Emily Esakov +5 more
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Transgenic mouse models for ADHD [PDF]
Cell and Tissue Research, 2013 Attention-deficit hyperactivity disorder (ADHD) is a developmental disorder characterized by symptoms of inattention, impulsivity and hyperactivity that adversely affect many aspects of life. Whereas the etiology of ADHD remains unknown, growing evidence indicates a genetic involvement in the development of this disorder.
Leo, Damiana, Gainetdinov, Raul R.
openaire +2 more sources
A transgenic tri-modality reporter mouse. [PDF]
PLoS ONE, 2013 Transgenic mouse with a stably integrated reporter gene(s) can be a valuable resource for obtaining uniformly labeled stem cells, tissues, and organs for various applications.
Xinrui Yan +7 more
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Transgenic fish and aquaculture [PDF]
, 1995 Transgenic fish species can be routinely produced by transferring foreign DNA into developing embryos via microinjection or electroporation. This technology offers an excellent opportunity for modifying or improving the genetic traits of commercially ...
Chen, Thomas T.
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Disease Models & Mechanisms, 2016 Histone deacetylase 9 (HDAC9) is expressed in B cells, and its overexpression has been observed in B-lymphoproliferative disorders, including B-cell non-Hodgkin lymphoma (B-NHL). We examined HDAC9 protein expression and copy number alterations in primary
Veronica S. Gil +8 more
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The changing role of cell culture in the generation of transgenic livestock [PDF]
, 1999 Transgenesis may allow the generation of farm animals with altered phenotype, animal models for research and animal bioreactors. Although such animals have been produced, the time and expense involved in generating transgenic livestock and then ...
Whitelaw, C B, Farini, E, Webster, J
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