Results 81 to 90 of about 3,961,294 (191)
Studies on plant gene transfer systems [PDF]
, 1989 A number of methods for the transfer of genes to plants are assessed in this work. The potential of Agrobacterium tumefaciens infection of germinating pollen tubes in vitro as a method of gene transfer was investigated and evidence presented for an ...
Sherman, Adrian
core
Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing
The Journal of Physiology, EarlyView.Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A, we used in silico models of human cardiomyocytes and microelectrode recordings on transgenic zebrafish hearts to study electrophysiology during optogenetic perturbations. Specifically, we compared effects of three distinct classes of channelrhodopsins: the cation non‐selective Chlamydomonas reinhardtii channelrhodopsin‐2 (ChR2)
Sophia Ohnemus +12 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 21, 12 November 2026.Can a single element help address the multifactorial nature of ALS? Boron‐containing compounds combine responsiveness to reactive oxygen species (ROS), neuroprotective activity, and favorable pharmacological properties, offering a distinctive framework for disease modification in a complex disease like ALS.
Nitesh Sanghai +5 more
wiley +1 more source
Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches
Analysis &Sensing, Volume 6, Issue 6, November 2026.The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi +2 more
wiley +1 more source
Mutagenitätsprüfung mit dem in vitro-TGRA: von Frequenzen zu Signaturen [PDF]
The in vitro Transgenic Rodent Assay (TGRA) using metabolically competent primary MutaMouse hepatocytes represents a novel method for detecting gene mutations.
Honarvar, Naveed +3 more
core +1 more source
The Anatomical Record, Volume 309, Issue 11, Page 3375-3396, November 2026.Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore +5 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 6, November 2026.ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan +3 more
wiley +1 more source
Glia, Volume 74, Issue 11, November 2026.Pathogenic variants alter hepaCAM protein distribution. Astrocyte‐specific hepaCAM TurboID reveals KCNQ2 as a new interaction partner. Pathogenic variants alter hepaCAM association with key transmembrane proteins. ABSTRACT Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare leukodystrophy characterized by early‐onset macrocephaly,
Robert W. Lewis +10 more
wiley +1 more source
Ets2 Is an Activity‐Dependent Transcriptional Regulator of a Fast‐Twitch Muscle Program
The FASEB Journal, Volume 40, Issue 20, 31 October 2026.Ets2 is a transcription factor rapidly (24 h) upregulated in skeletal muscle by fast 150 Hz, but not slow 20 Hz, stimulation patterns. Ets2 selectively translocates to nuclei of slow soleus muscle when stimulated by fast‐patterned, but not slow‐patterned, activity. Ets2 binds to a consensus DNA sequence in the troponin I fast intronic enhancer (TnIFIRE)
Zaheer A. Rana +9 more
wiley +1 more source