Results 111 to 120 of about 24,604,955 (198)
Objective To explore the role and mechanism of exosomes derived from bone marrow mesenchymal stem cells (BMSCs) overexpressing transglutaminase 2 (TGM2) in lactate-mediated oxidative stress-induced apoptosis in nucleus pulposus cells.
LOU Jinhui, GAO Xiaoxin, ZHANG Yuyao
doaj +1 more source
Immune‐related adverse events with mogamulizumab in cutaneous T‐cell lymphoma: A multicentre study
In a nationwide multicentre study of 403 patients with cutaneous T‐cell lymphoma treated with mogamulizumab, non‐MAR immune‐related adverse events were reported in 8.4% of patients across responding centres. These events were diverse, sometimes severe or persistent, and could occur late during mogamulizumab treatment.
David Neubauer +28 more
wiley +1 more source
Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
Deamidated Gliadin Peptides Form Epitopes That Transglutaminase Antibodies Recognize
Objective: Deamidated gliadin peptides are efficient antigens in diagnostic tests for celiac disease, and results correlate better with transglutaminase 2-based assays than those with native gliadin.
Korponay-Szabó, Ilma R., +9 more
core +1 more source
The activity of transglutaminase (TGase), an enzyme responsible for polyamine conjugation to proteins, was analysed in relationship to developmental cell death (DCD) during the flower life span stages of the Nicotiana tabacum corolla. As the DCD exhibits
DELLA MEA, MASSIMILIANO +4 more
core +1 more source
Objectives: Cancer cells with ‘stemness’ are generally resistant to chemoradiotherapy. This study aims to compare the differences in radiation sensitivity of A549 and CD44+A549 stem-like cells to X-rays and carbon ion radiation (C-ions), and to find a ...
Qian Wang +12 more
doaj +1 more source
Site‐specific O‐glycans influence lacritin structure and multimerization in tears
Abstract Lacritin is an abundantly expressed glycoprotein in tear fluid and plays key roles in immune response, tear secretion, and bacterial killing. These biological functions are tightly regulated through several biochemical mechanisms including multimerization, proteolysis, and alternative splicing, especially within its C‐terminal domain.
Vincent Chang +7 more
wiley +1 more source
The role of Transglutaminase Type 2 in Breast Cancer
reservedTransglutaminase Type 2 (TG2), member of the Mammalian Transglutaminase family, is a multi-functional and widely distributed protein localized in the cytosol, in the nucleus, in mitochondria, on the plasma membrane, and in the extracellular ...
GENOVESE, CHIARA
core
Complex microarchitectures emerge from simple flow‐driven transformations as static mixers iteratively reorient and split material domains. Coupled with diverse deposition strategies, chaotic printing provides an accessible platform for fabricating architected materials that support biologically and chemically relevant processes. ABSTRACT Nature builds
Edna Johana Bolívar‐Monsalve +7 more
wiley +1 more source
Schematic representation of artificial intelligence approaches in enzyme catalysis, integrating bibliometric analysis, emerging research trends, and machine learning tools for enzyme design, prediction, and industrial biocatalytic applications. Abstract This study systematically explores the applications of artificial intelligence (AI) in enzyme ...
Misael Bessa Sales +6 more
wiley +1 more source

