Results 121 to 130 of about 24,604,955 (198)

Ethnomedicinal Uses of Thai Legumes (Fabaceae) and Their Potential in Industrial Applications

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
Thai legumes (Fabaceae) are rich sources of bioactive phytochemicals, including saponins, flavonoids, biochanin A, and daidzein. These compounds contribute to diverse ethnomedicinal properties, including antioxidant, antiviral, anti‐inflammatory, anticancer, and cardioprotective activities.
Muhammad Tayyab Arshad   +7 more
wiley   +1 more source

Glutamine Metabolism in Health and Diseases

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding   +3 more
wiley   +1 more source

Significance of the Syndecan-4-Transglutaminase-2 Interaction [PDF]

open access: yes, 2010
Alessandra Scarpellini   +3 more
core   +1 more source

Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song   +4 more
wiley   +1 more source

Immunoglobulin a Deficiency in Coeliac Disease: A Scoping Review

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 8, October 2026.
ABSTRACT Coeliac disease (CeD) and immunoglobulin A deficiency (IgAD) frequently co‐occur and share a genetic background within the HLA‐DQ2 region. Although this has been known for decades, the underlying mechanisms linking the two conditions remain unclear.
Kristine Bech   +4 more
wiley   +1 more source

A comprehensive approach to elucidating the pathophysiology of kidney fibrosis based on extracellular vesicle proteomics

open access: yesFrontiers in Physiology
IntroductionTransglutaminase 2 (TG2) plays a profibrotic role in chronic kidney disease (CKD), but its role in the exosomal proteome remains unexplored.
Yaerim Kim   +16 more
doaj   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

open access: yesActa Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

Long‐Term Follow‐Up Incidence of Type 1 Diabetes and Associated Autoimmune Diseases in First‐Degree Relatives

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9668-9679, October 2026.
ABSTRACT Background First‐degree relatives (FDRs) of individuals with type 1 diabetes (T1D) carry a significantly elevated risk of developing autoimmune diseases, including celiac disease (CD) and autoimmune thyroid disease (AITD). The DiaUnion 1.0 study aimed to characterize one‐time autoantibodies, genetic risk profiles and long‐term progression to ...
Julie H. Christensen   +9 more
wiley   +1 more source

Discovery of Post‐Translationally Modified Epitopes in Autoimmunity: Someone Has to Fish so Everyone Can Eat

open access: yesImmunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT Post‐translational modifications (PTMs) chemically diversify the ~20,000 genomically encoded proteins into millions of functional variants, and this diversity has profound consequences for T cell‐mediated immune responses. PTM‐reactive T cells have been identified across numerous autoimmune diseases and, in several cases, implicated directly ...
Sanya Arshad   +2 more
wiley   +1 more source

Beta Cell Stress to Epitope Diversification: Post‐Translationally Modified Antigens in Type 1 Diabetes

open access: yesImmunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT Pancreatic beta cells are active participants in the loss of immune tolerance because their high secretory demand creates exceptional vulnerability to inflammatory exposure, endoplasmic reticulum (ER) stress, calcium dysregulation, and redox imbalance. These conditions can promote enzymatic and nonenzymatic changes in self‐proteins, generating
Megan L. Proffer   +2 more
wiley   +1 more source

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