Results 131 to 140 of about 24,604,955 (198)

Transcriptomic Dynamics Associated With In Vitro Oocyte Competence in Pigs

Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.
ABSTRACT Porcine in vitro embryo production (pIVP) would have a major impact on both livestock production and biomedical research if its efficiency—currently limited by suboptimal oocyte competence—could be improved. This study aimed to characterize transcriptional dynamics across oocyte in vitro maturation (IVM) and fertilization (IVF).
D. Gascón‐Collado, C. G. Cabrera‐Gomez, P. Blanco‐Cueto, H. Rodriguez‐Martinez, C. A. Martinez‐Serrano   +4 more
wiley   +1 more source

Toward celiac-safe foods - Investigation of the interaction between transglutaminase 2 and gluten [Elektronisk resurs]

, 2018
Celiac disease, a chronic autoimmune enteropathy, may develop in genetically predisposed individuals upon ingestion of gluten proteins found in wheat, barley, and rye.
Engström, Niklas,
core  

Artificial Intelligence and Virtual Screening to Identify Small Molecules Inhibiting Transglutaminase 2 for Investigation and Treatment of Breast Cancer

ChemBioChem, Volume 27, Issue 18, 28 September 2026.
Artificial Intelligence (AI)‐guided screening of nearly 10 million molecules hit the bull’s‐eye: G11, a new nonpeptidic inhibitor of transglutaminase 2. A stepwise path from in silico ranking to cell and biochemical assays identified G11 as the top hit. It induced apoptosis in transglutaminase 2 (TG2)‐rich breast cancer cells and inhibited purified TG2,
Carlo M. Bergamini, Niel M. Henriksen, Brianna Ryan, Taylor A. Prince, Anna Terrazzan, Pietro Ancona, Cristina Zuccato, Gianluca Aguiari, Valentina Rosta, Jeffrey W. Keillor, Alessandro Trentini, Nicoletta Bianchi   +11 more
wiley   +1 more source

The role of transglutaminase 2 in stabilizing fibrin clots and supporting hemostasis. [PDF]

PLoS One
Stoklosa P, Suzuki R, Golomingi M, Li B, Heller M, Hitomi K, Hardy ET, Lam WA, Schroeder V.   +8 more
europepmc   +1 more source

Transglutaminase 2 regulates vimentin-dependent proteostasis during macrophage activation. [PDF]

Sci Adv
Xu Y, Su T, Mishra H, Dohmae N, Suzuki T, Sakamaki Y, Aoyagi H, Aizaki H, Nishimura H, Furuhata E, Gong Y, Cheng Q, Zhang B, He C, Yanaka K, Furutani Y, Tatsukawa H, Suzuki H, Yu W, Qin XY.   +19 more
europepmc   +1 more source

OV16 Improves Radiation-Induced Intestinal Injury by Targeting Transglutaminase 2. [PDF]

Molecules
Zhang Z, Wang H, Cui Y, Lu Y, Xu Y, Li M, Liu S, Tian Y, Xia Z, Zhang G, Liu S.   +10 more
europepmc   +1 more source

Cryo-EM structure of the complex between transglutaminase 2 and the 45 kDa domain of fibronectin. [PDF]

J Biol Chem
Heggelund JE, Ali-Ahmad A, Johannesen MK, Sekulić N, Sollid LM.   +4 more
europepmc   +1 more source

Transglutaminase 2 regulates innate immunity: mechanisms and therapeutic implications. [PDF]

Oncoimmunology
D'Eletto M, Occhigrossi L, Colasuonno F, Bellanca V, Di Sano F, Montesano C, Ciccosanti F, Shi Y, Piacentini M, Rossin F.   +9 more
europepmc   +1 more source

Targeting injury-induced transglutaminase-2 activity with a cementoin-SLPI fusion protein: a novel therapeutic strategy for alkali-induced corneal injury. [PDF]

J Transl Med
Salica JP, Potilinski C, Ortiz G, Guerrieri D, Maffia PC, Chuluyan E, Gallo JE.   +6 more
europepmc   +1 more source

Association of transglutaminase-2 with contrast-induced acute kidney injury in Chinese patients with acute coronary syndrome: a prospective cohort study. [PDF]

Ann Med
Yao R, Zhang J, Zhang W, Qin Y, Qiao Y, Wang D, Yan G, Tang C.   +7 more
europepmc   +1 more source