Results 121 to 130 of about 4,824 (245)
TGM1/3-mediated transamidation of Exo70 promotes tumor metastasis upon LKB1 inactivation
Summary: Exo70, a key exocyst complex component, is crucial for cell motility and extracellular matrix (ECM) remodeling in cancer metastasis. Despite its potential as a drug target, Exo70’s post-translational modifications (PTMs) are poorly characterized.
Jihuan Hou +17 more
doaj +1 more source
ABSTRACT A key bottleneck in the development of octopus aquaculture is the absence of formulated feeds that are readily consumed and fulfil their nutritional requirements. Until efficacious formulated feeds are developed, sustainably‐sourced natural seafood diets provide a potential viable alternative for octopus aquaculture.
Stefan Spreitzenbarth +6 more
wiley +1 more source
Excitotoxic and post-ischemic neurodegeneration: Involvement of transglutaminases
Neurodegeneration induced by excitotoxicity is a common feature in various neurological disorders. This pathological condition is caused by prolonged stimulation of glutamate receptor subtypes, followed by both intracellular Ca2+ overload and activation ...
VANELLA A +10 more
core +1 more source
Pea Protein Extraction Techniques: A Comparative Study With Commercial Pea and Soy Proteins
ABSTRACT Two common methods used to separate plant‐based proteins are wet extraction and dry fractionation. To identify the most suitable industrial applications, this study investigated the effects of wet extraction and dry fractionation on the physicochemical and functional properties of the Australian yellow field pea proteins, comparing them ...
Anahita Sharifi +5 more
wiley +1 more source
Integrated circular biorefinery concept coupling fruit‐processing residue valorization with renewable H2‐powered CO2 fixation for sustainable, food‐grade single‐cell protein production. ABSTRACT The conversion of agricultural residues into food‐grade single‐cell protein (SCP) has emerged as a promising strategy to simultaneously address increasing ...
Gebeyehu Ayele +4 more
wiley +1 more source
This study explores the discrepancies between bulk mechanics and spatial mapping in a tissue‐mimetic hydrogel model. Microplastic particles create localized stiff mechanical microenvironments that are detectable by cellular‐scale nanoindentation but leave bulk properties unchanged as measured by rheology.
Ahron T. Verschleisser +3 more
wiley +1 more source
Transglutaminases are ubiquitous enzymes which catalyze posttranslational modifications of proteins. Recently, transglutaminase-catalyzed post-translational modification of proteins has been shown to be involved in the molecular mechanisms responsible ...
Giulia De Vivo +5 more
core +1 more source
Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng +20 more
wiley +1 more source
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy +7 more
wiley +2 more sources
Enhanced Chemiluminescent Assay for Transglutaminases
Komandoor E. Achyuthan
doaj +1 more source

