Results 101 to 110 of about 4,824 (245)

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Transglutaminases: key regulators of cancer metastasis

, 2013
The ability to metastasize represents the most important characteristic of malignant tumors. The biological details of the metastatic process remain somewhat unknown, due to difficulties in studying tumor cell behaviour with high spatial and temporal ...
Beninati, S, Lentini, A, Provenzano, B, PROVENZANO, BRUNO, BENINATI, SIMONE, Abbruzzese, A, LENTINI, ALESSANDRO, Tabolacci, C   +7 more
core   +1 more source

Cystamine preparations exhibit anticoagulant activity.

PLoS ONE, 2015
Transglutaminases are a superfamily of isoenzymes found in cells and plasma. These enzymes catalyze the formation of ε-N-(γ-glutamyl)-lysyl crosslinks between proteins.
Maria M Aleman, Lori A Holle, Katherine G Stember, Christa I Devette, Dougald M Monroe, Alisa S Wolberg   +5 more
doaj   +1 more source

Development of a Clinical and Biomarker‐Based Score to Predict Microscopic Colitis in Patients With Chronic Watery Diarrhoea

Alimentary Pharmacology &Therapeutics, EarlyView.
The MC‐fCAL score combines simple clinical variables and faecal calprotectin to predict microscopic colitis in patients with chronic watery diarrhoea. It showed promising diagnostic accuracy and may support future risk‐stratified diagnostic pathways by identifying patients with a low estimated probability or a strong suspicion of microscopic colitis ...
Laura Ruiz‐Campos, Yamile Zabana, Lissette Batista, Danila Guagnozzi, Ingrid Fajardo, Pablo Ruiz‐Ramírez, Carme Loras, Maria Esteve, Fernando Fernández‐Bañares   +8 more
wiley   +1 more source

Prevalence and clinical features of celiac disease in patients with autoimmune thyroiditis: cross-sectional study

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Celiac disease is an autoimmune disorder with an average prevalence of 1% in Europe and the United States. Because of strong European ancestry in southern Brazil, this study aimed to evaluate the seroprevalence of celiac disease ...
Aline Ventura, Marcelo Fernando Ronsoni, Maria Beatriz Cacese Shiozawa, Esther Buzaglo Dantas-Corrêa, Maria Heloisa Busi da Silva Canalli, Leonardo de Lucca Schiavon, Janaína Luz Narciso-Schiavon   +6 more
doaj   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Cofactors in Anaphylaxis: Insights From the European Anaphylaxis Registry

Clinical &Experimental Allergy, EarlyView.
Forty‐nine per cent of reactions reported suspected cofactors (26% of children/adolescents, 59% of adults). Adjusted odds ratios for reaction severity increased with increasing number of suspected cofactors. Consistent effects for individual suspected cofactors were only observed for acute infections (children) and alcohol (adults with food‐induced ...
Margitta Worm, Sabine Dölle‐Bierke, Guillaume Pouessel, Franziska Ruëff, Karin Hartmann, Claudia Pföhler, Maria Beatrice Bilò, Nicola Wagner, Nikolaos G. Papadopoulos, Lars Lange, Andrea Bauer, Johannes Trück, Paul J. Turner, Veronika Höfer   +13 more
wiley   +1 more source

Transglutaminases expression in human supraspinatus tendon ruptures and in mouse tendons.

, 2009
The ethiopathogenesis of rotator cuff disease remains poorly understood. Many studies advocate the importance of extra cellular matrix for the homeostasis of connective tissue. Transglutaminase enzymes family has been studied in the context of connective
Oliva,F, Zocchi,L, Melino,G, Celi, M, Candi,E, MELINO, GENNARO, Oliva, F, Codispoti, A, Maffulli, N, MAFFULLI, Nicola, Tarantino,U, E. Candi, U. Tarantino, L. Zocchi, M. Celi, Melino, G, OLIVA, Francesco, Codispoti,A, Candi, E, Maffulli,N, CANDI, ELEONORA, Tarantino, U, G. Melino, A. Codispoti, TARANTINO, UMBERTO, Celi,M, Zocchi, L   +26 more
core   +1 more source

A De Novo ATP1A3 p.Arg995His Variant in a Patient With an Adult‐Onset Primary Lateral Sclerosis‐Like Syndrome

Clinical Genetics, EarlyView.
A 43‐year‐old woman developed a progressive adult‐onset upper motor neuron syndrome fulfilling the clinical criteria for primary lateral sclerosis (PLS), with mild cerebellar involvement. Genetic testing identified a de novo ATP1A3 p.Arg995His variant affecting a highly conserved residue within the transmembrane M8 domain.
Pablo Hernandez‐Vitorique, Marta García de Burgos, Ana Campos Villegas, María José Gómez Heredia, Pilar Carbonell Corvillo   +4 more
wiley   +1 more source

LC‐OCT of Dermatitis Herpetiformis

JEADV Clinical Practice, EarlyView.
Daniele Omar Traini, Gerardo Palmisano
wiley   +1 more source