Results 81 to 90 of about 7,007 (263)
Transglutaminases (TGs) in ocular and periocular tissues: effect of muscarinic agents on TGs in scleral fibroblasts. [PDF]
PLoS ONE, 2011 OBJECTIVE: To investigate the expression of transglutaminases (TGs) in the ocular surface, the eyelid margin and associated glands and to determine effect of muscarinic agents on TGs in scleral fibroblasts (SF).
V A Barathi +5 more
doaj +1 more source
Enzyme-catalyzed protein crosslinking [PDF]
, 2018 The process of protein crosslinking comprises the chemical, enzymatic, or chemoenzymatic formation of new covalent bonds between polypeptides. This allows (1) the site-directed coupling of proteins with distinct properties and (2) the de novo assembly of
Faccio, Greta +3 more
core
, 2010 Putrescine (1,4-diaminobutane) was covalently linked to alginate and low-methoxyl pectin to synthesize new aminated polysaccharides. Both putrescine-pectin and -alginate conjugates, although the latter at higher concentrations, were found to be able to ...
CHICO B. +5 more
core +1 more source
The oomycete microbe-associated molecular pattern Pep-13 triggers SERK3/BAK1-independent plant immunity [PDF]
, 2019 To prevent disease, pattern recognition receptors (PRRs) are responsible for detecting microbe-associated molecular patterns (MAMPs) to switch on plant innate immunity.
Birch, Paul R. J. +6 more
core +2 more sources
Effect of Escherichia coli endotoxin on Archachatina marginata haemolymph coagulation system [PDF]
, 2010 The effect of _E. coli_ endotoxin on the heamolymph coagulation response of _Archachatina marginata_ was studied. Heamocyte Lysate(HL), Haemocyte Lysate Supernatant(HLS) and Haemocyte Lysate Debris (HLD) were exposed to _Escherichia coli_ endotoxin ...
Adenike Oladiji +4 more
core +1 more source
Porcine intestinal epithelial barrier disruption by the Fusarium mycotoxins deoxynivalenol and T-2 toxin promotes transepithelial passage of doxycycline and paromomycin [PDF]
, 2012 Background: The gastrointestinal tract is the first target for the potentially harmful effects of mycotoxins after intake of mycotoxin contaminated food or feed.
Croubels, Siska +8 more
core +2 more sources
iMetaMed, EarlyView.Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen +4 more
wiley +1 more source
Journal of the Chinese Chemical Society, EarlyView.This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel +2 more
wiley +1 more source
Haptoglobin Polymorphism: A Novel Genetic Risk Factor for Celiac Disease Development and Its Clinical Manifestations [PDF]
, 2008 Background: Haptoglobin (Hp) α-chain alleles 1 and 2 account for 3 phenotypes that may influence the course of inflammatory diseases via biologically important differences in their antioxidant, scavenging, and immunomodulatory properties.
Altorjay, István +17 more
core +1 more source
The “5L” framework of diagnostic reasoning: A stepwise scaffold to support clinician educators
Journal of Hospital Medicine, EarlyView.Abstract Diagnostic reasoning (DR) is a core clinical skill, yet its teaching remains variable. We introduce the “5L” framework as a bedside teaching scaffold that gives educators and learners a shared, stepwise set of prompts for DR during individual encounters. By asking, “What's Lethal? What's Likely? What's Logical? What's Lurking?
Olivia Brumfield +3 more
wiley +1 more source