Pseudomurein endoisopeptidases PeiW and PeiP, two moderately related members of a novel family of proteases produced in Methanothermobacter strains [PDF]
Sequence comparison of pseudomurein endoisopeptidases PeiW encoded by the defective prophage ΨM100 of Methanothermobacter wolfeii, and PeiP encoded by phage ΨM2 of Methanothermobacter marburgensis, revealed that the two enzymes share only limited ...
Leisinger, Thomas +3 more
core
The over-expression of the plastidial transglutaminase from maize in Arabidopsis increases the activation threshold of photoprotection [PDF]
Plastidial transglutaminase is one of the most promising enzymes in chloroplast bioenergetics due to its link with polyamine pathways and the cross talk with signals such as Ca2+ and GTP.
Ioannidis, Nikolaos E. +4 more
core +3 more sources
Abstract Objectives Our aim was to study the association between residential land cover and greenness during childhood and risk of developing celiac disease (CeD). Methods The Celiac Prediction in Skåne study prospectively followed 5969 human leukocyte antigen (HLA)‐genotyped children born 2001–2004 who were screened for CeD at ages 3, 9, and 15 years ...
Michaela Boström +6 more
wiley +1 more source
Serotonylation: Serotonin Signaling and Epigenetics
Serotonylation, the covalent linkage of serotonin to proteins has been discovered more than 60 years ago but only recently the mechanisms and first functions have been elucidated.
Michael Bader +3 more
doaj +1 more source
Revisiting the mechanism of coagulation factor XIII activation and regulation from a structure/functional perspective [PDF]
The activation and regulation of coagulation Factor XIII (FXIII) protein has been the subject of active research for the past three decades. Although discrete evidence exists on various aspects of FXIII activation and regulation a combinatorial structure/
A Biswas +66 more
core +1 more source
The needle study: Machine learning as a new method for case‐finding in celiac disease
Abstract Objectives Despite a well‐defined diagnostic work‐up, uncertainties persist regarding celiac disease (CeD) detection strategies in the general population. Machine learning (ML) algorithms offer promise in aiding medical decision‐making on clinical data.
Chiara Maria Trovato +9 more
wiley +1 more source
Alcohol Induces Sensitization to Gluten in Genetically Susceptible Individuals: A Case Control Study [PDF]
Background: The mechanisms of cerebellar degeneration attributed to prolonged and excessive alcohol intake remain unclear. Additional or even alternative causes of cerebellar degeneration are often overlooked in suspected cases of alcohol-related ataxia.
A Floreani +53 more
core +2 more sources
Emulsion type governed the microstructure and functionality of papers coated with biopolymers matrix loaded with hydrophobic bioactives encapsulated into O/W emulsions. Emulsified systems improved UV–Vis barrier and antioxidant activity, whereas gelatin coatings with conventional or Pickering emulsions provided the greatest mechanical reinforcement ...
Kamila de L. Santos +4 more
wiley +1 more source
DNAJA1 as a novel interacting partner of transglutaminase 2 [PDF]
Transglutaminase 2 (TG2) is a multifunctional enzyme which participates in posttranslational modification of proteins, such as catalyzing calcium dependent crosslinking of proteins, incorporation of primary amines and deamidation of proteins.
Ergülen, Elvan
core
P2X7 receptor-mediated TG2 externalization: a link to inflammatory arthritis? [PDF]
Transglutaminases have important roles in stabilizing extracellular protein assemblies in tissue repair processes but some reaction products can stimulate immune activation, leading to chronic inflammatory conditions or autoimmunity.
Aeschlimann, Daniel, Knauper, Vera
core +1 more source

