Results 121 to 130 of about 4,038,778 (298)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Wideband Monitoring of FRB 20180916B across a Half Decade of Bandwidth Using the Upgraded GMRT

open access: yesThe Astrophysical Journal
With the upgraded Giant Metrewave Radio Telescope (uGMRT) having unprecedented sensitivity and unique capability of providing instantaneous frequency coverage of 250−1460 MHz, we studied FRB 20180916B with 4 month sampling during its active phase.
Siddhartha Bhattacharyya   +2 more
doaj   +1 more source

Transient-locked saccade onset times.

open access: yes
(A) Same as in Fig 1C, but showing the distribution of saccade onset times locked to the time of transient (blank onset), pooled across participants, in the orientation change detection task.
Devarajan Sridharan (416446)   +1 more
core   +1 more source

Franks, Theodore

open access: yes, 2021
Transient application card documenting relief requests and authorizations to the destitute by Transient Bureau of Kalamazoo County, under the Federal Emergency Relief Administration, May 1933 - June ...
Kalamazoo County (Mich.). Transient Bureau
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Transient response enhancement method for DC-DC converters based on adaptive duty cycle adjustment

open access: yesAin Shams Engineering Journal
This article presents an adaptive duty cycle adjustment DC-DC converter for improving load transient response. The combination of adaptive clock control and DAC output variable reference voltage allows for rapid duty cycle saturation to further increase ...
Zhongjie Guo   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Kilonova Constraints for the LIGO/Virgo/KAGRA Neutron Star Merger Candidate S250206dm: GW-MMADS Observations

open access: yesThe Astrophysical Journal Letters
Gravitational-wave (GW) neutron star mergers with an associated electromagnetic counterpart constitute powerful probes of binary evolution, the production sites of heavy elements, general relativity, and the expansion of the Universe.
Lei Hu   +37 more
doaj   +1 more source

Bain, Homer

open access: yes, 2021
Transient application card documenting relief requests and authorizations to the destitute by Transient Bureau of Kalamazoo County, under the Federal Emergency Relief Administration, May 1933 - June ...
Kalamazoo County (Mich.). Transient Bureau
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

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