Results 101 to 110 of about 1,668,806 (304)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Transient Response Enhancement of PMD Battery Charger Using Rule-Based Fuzzy Logic Control

Mathematics
This paper proposes a transient response enhancement of a personal mobility device (PMD) battery charger using a rule-based fuzzy logic control (RBFLC) method.
Gijeong Yoon, Yeongsu Bak
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Rotor response for transient unbalance changes in a nonlinear simulation [PDF]

Transient unbalance shifts were determined not to excite a rotor instability in the high pressure turbomachinery of the Space Shuttle Main Engine using the current rotor dynamic models.
Beatty, R. F., Hine, M. J., Landis, C. E.   +2 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Understanding the influence of cation and anion migration on perovskite light-emitting diodes via transient response. [PDF]

Sci Rep, 2023
Forozi Sowmeeh P, Zohorfazeli M, Yazdani E.   +2 more
europepmc   +1 more source

Analysis of the transient calibration of heat flux sensors: One dimensional case [PDF]

The effect of transient heat flux on heat flux sensor response and calibration is analyzed. A one dimensional case was studied in order to elucidate the key parameters and trends for the problem.
Dybbs, A., Ling, J. X.
core   +1 more source

Transient response measurements on a satellite system [PDF]

, 1977
A set of instruments designed to detect the occurance of electrical breakdown was flown on a synchronous-orbit satellite. The LeRC sensors were installed on cables inside the vehicle. Accordingly, they respond to signals coupled into the satellite wiring
Adamo, R. C., Nanevicz, J. E.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Broadband Transient Response and Wavelength-Tunable Photoacoustics in Plasmonic Hetero-nanoparticles. [PDF]

Nano Lett, 2023
Bykov AY, Xie Y, Krasavin AV, Zayats AV.
europepmc   +1 more source