Results 111 to 120 of about 6,392,109 (288)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Rapid Fault-Tolerant MPC Strategy for Six-Phase PMSMs: Optimizing Torque Stability, Current Constraint Management During Phase Transition

IEEE Access
Six-phase permanent magnet synchronous machines (PMSMs) provide improved fault tolerance and reliability, making them well-suited for critical applications like aerospace and hybrid electric vehicle systems.
Peter Nkwocha Harmony, Ahmed H. Okilly, Cheolgyu Kim, Do-Wan Kim, Seungdeog Choi, Jeihoon Baek   +5 more
doaj   +1 more source

Transient Response and Firing Behaviors of Memristive Neuron Circuit. [PDF]

Front Neurosci, 2022
Fang X, Tan Y, Zhang F, Duan S, Wang L.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Carson, John J.

, 2021
Transient application card documenting relief requests and authorizations to the destitute by Transient Bureau of Kalamazoo County, under the Federal Emergency Relief Administration, May 1933 - June ...
Kalamazoo County (Mich.). Transient Bureau
core  

Application of fuzzy controllers in the autopilot of an unmanned aerial vehicle

Системный анализ и прикладная информатика
The article is devoted to the study of the features of the application of regulators built on the use of theoretical provisions of fuzzy logic, when creating autopilots of unmanned aerial vehicles (UAVs).
Penghao Gu, A. A. Lobaty
doaj   +1 more source

Transient response of bridge piers under eccentric impact of near-fault earthquake. [PDF]

Sci Rep, 2022
Wang Z, Zeng Q, Du Y, An W.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Bain, Homer

, 2021
Transient application card documenting relief requests and authorizations to the destitute by Transient Bureau of Kalamazoo County, under the Federal Emergency Relief Administration, May 1933 - June ...
Kalamazoo County (Mich.). Transient Bureau
core  

The Transient Response of a Disk Electrode [PDF]

Journal of The Electrochemical Society, 1973
Nisancioglu, Kemal, Newman, John.
openaire   +2 more sources