Results 131 to 140 of about 854,868 (315)

Leak detection using instantaneous frequency analysis [PDF]

, 2012
Leaking pipes are a primary concern for water utilities around the globe as they compose a major portion of losses. Contemporary interest surrounding leaks is well documented and there is a proliferation of leak detection techniques. Although the reasons
M. F., Ghazali, ghazali, mohd fairusham
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A review on the mechanism of high repetition rate pulse interference on the RF front-end of GNSS receivers

Frontiers in Physics
With the rapid advancement of pulse technology, given the extraordinarily high repetition frequency of high-repetition pulse interference, with pulse widths typically ranging from a few nanoseconds to several hundred nanoseconds, it possesses ultra ...
Yili Song, Yili Song, Huilin Wang, Wenxiang Liu, Wenxiang Liu, Wei Xiao, Wei Xiao, XiaoZhou Ye, XiaoZhou Ye, Guangfu Sun, Guangfu Sun   +10 more
doaj   +1 more source

Transient Response of Miniature Piezoresistive Pressure Sensor Dedicated to Blast Wave Monitoring. [PDF]

Sensors (Basel), 2022
Sanchez K, Achour B, Coustou A, Lecestre A, Charlot S, Lavayssière M, Lefrançois A, Aubert H, Pons P.   +8 more
europepmc   +1 more source

Controllability of road vehicles at the limits of tyre adhesion [PDF]

, 1998
The research project 'Controllability of Road Vehicles at the Limits of Tyre Adhesion' (CROVLA) was established to investigate how tyre and chassis properties contribute to the handling characteristics and stability of vehicles operating at or near to ...
Kohn, H.J., Kohn, Heinz Joachim
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Enhanced Low‐Voltage Ride‐Through Capability of DFIG by Explicit Model Predict Control Based Decoupled Virtual Impedance

IET Renewable Power Generation
The power grid requires doubly‐fed induction generators (DFIGs) to effectively suppress rotor currents and provide reactive power support during low voltage ride‐through (LVRT) events.
Jia Luo, Haoran Zhao, Peng Wang
doaj   +1 more source

Transient Response and Firing Behaviors of Memristive Neuron Circuit. [PDF]

Front Neurosci, 2022
Fang X, Tan Y, Zhang F, Duan S, Wang L.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source