Results 81 to 90 of about 1,668,806 (304)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Time-dependent screening of a positive charge distribution in metals: Excitons on an ultra-short time scale

open access: yes, 2000
Experiments determining the lifetime of excited electrons in crystalline copper reveal states which cannot be interpreted as Bloch states [S. Ogawa {\it et al.}, Phys. Rev. B {\bf 55}, 10869 (1997)].
A. G. Eguiluz   +26 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Study on the Transient Response of Lower Limb Rehabilitation Actuator Using the Pneumatic Cylinder [PDF]

open access: yes, 2018
A lower limb rehabilitation device was designed using the compressed air cylinder in order to answer the particular request in Vietnam. This paper is presenting the results of a study of the device response. Dynamic equation of the actuator and equations
Dao, D. M. (Duc)   +3 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Dynamic analysis using finite element method for a nonlinear spring-supported disk: Technique to reduce second-order distortion due to diaphragm shape

open access: yesMechanical Engineering Journal, 2017
This research aims to reduce the second-order distortion due to diaphragm vibration. The quadratic term of the restoring force of nonlinear springs varies in the pulling and compression directions.
Mitsuharu WATANABE   +4 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Transient Behavior Analysis of Offshore Wind Turbines During Lightning Strike to Multi-Blade

open access: yesIEEE Access, 2018
A set of analytic formulas are presented to evaluate the circuit parameters of blade, tower, three-phase cable, and monopile foundation. On the basis of the circuit parameters, the circuit model is built and a transient analysis is carried out for the ...
Shiqi Tao   +3 more
doaj   +1 more source

Blade loss transient dynamics analysis, volume 2. Task 2: TETRA 2 user's manual [PDF]

open access: yes
This is the user's manual for the TETRA 2 Computer Code, a program developed in the NASA-Lewis Blade Loss Program. TETRA 2 calculates a turbine engine's dynamic structural response from applied stimuli. The calculation options are: (1) transient response;
Black, Gerald, Gallardo, Vincente C.
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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