Results 101 to 110 of about 355,526 (290)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Transient stability index for online stability assessment and contingency evaluation

International Journal of Electrical Power & Energy Systems, 1982
Abstract An online methodology is proposed for assessing the robustness of a power system from the point of view of transient stability, and a scalar expression, the transient stability index, is accordingly derived. The reliability and sensitivity of this index are tested by means of simulations for a number of power system cases. The index is shown
M. Ribbens-Pavella, P.G. Murthy, J.L. Horward, J.L. Carpentier   +3 more
openaire   +1 more source

Experimental evaluation of a breadboard heat and product-water removal system for a space-power fuel cell designed with static water removal and evaporative cooling [PDF]

A test program was conducted to evaluate the design of a heat and product-water removal system to be used with fuel cell having static water removal and evaporative cooling. The program, which was conducted on a breadboard version of the system, provided
Hagedorn, N. H., Prokipius, P. R.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Transient Stability-Based Fast Power System Contingency Screening and Ranking

Electricity
Today’s power systems are operated closer to their stability limits due to the continuously growing load demands, interface to open markets, and integration of more renewable energies.
Teshome Lindi Kumissa, Fekadu Shewarega
doaj   +1 more source

Wide-Area Measurement—Based Model-Free Approach for Online Power System Transient Stability Assessment

Energies, 2018
Online assessment of transient stability of power systems is critical for avoiding blackout. The increasing installation of phasor measurement units in power systems and the advancement of the wide-area measurement systems make it possible to develop ...
Dan Huang, Qiyu Chen, Shiying Ma, Yichi Zhang, Shuyong Chen   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Transient Voltage Stability Assessment Method Based on CWT-ResNet

Energies
Accurate and rapid transient voltage stability assessment is crucial for the safe and stable operation of new energy bases in desert and grassland regions.
Chong Shao, Yongsheng Jin, Bolin Zhang, Xin He, Chen Zhou, Haiying Dong   +5 more
doaj   +1 more source

Characterizing water quality and hydrologic properties of urban streams in central Virginia [PDF]

, 2019
The objective of this study was to characterize water quality and hydrologic properties of urban streams in the Richmond metropolitan area. Water quality data were analyzed for six urban sites and two non-urban sites.
Lucas, Rikki
core   +1 more source