Results 81 to 90 of about 355,526 (290)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Power system stochastic transient stability assessment based on Monte Carlo simulation

open access: yesThe Journal of Engineering, 2018
Electrical power system is a complicated dynamic system with plenty of random disturbances while this character has been aggravated attributed to the rapid development of renewable energy technology.
Jiayu Liu   +4 more
doaj   +1 more source

An Improved Power System Transient Stability Prediction Model Based on mRMR Feature Selection and WTA Ensemble Learning

open access: yesApplied Sciences, 2020
Fast online transient stability assessment (TSA) is very important to maintain the stable operation of power systems. However, the existing transient stability assessment methods suffer the drawbacks of unsatisfactory prediction accuracy, difficult ...
Jun Liu   +4 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Empirical evaluation of accuracy of mathematical software used for availability assessment of fault-tolerant computer systems [PDF]

open access: yes, 2012
Dependability assessment is typically based on complex probabilistic models. Markov and semi-Markov models are widely used to model dependability of complex hardware/software architectures.
Kharchenko, V. S.   +3 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Improving predictive power of physically based rainfall-induced shallow landslide models: a probabilistic approach

open access: yes, 2014
Distributed models to forecast the spatial and temporal occurrence of rainfall-induced shallow landslides are based on deterministic laws. These models extend spatially the static stability models adopted in geotechnical engineering, and adopt an ...
Alvioli, M.   +5 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Survivability : A Unifiying Concept for the Transient Resilience of Deterministic Dynamical Systems [PDF]

open access: yes, 2015
16 pagesNon peer ...
Grabow, Carsten   +4 more
core   +1 more source

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