Results 81 to 90 of about 93,389 (292)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Application of swallowtail catastrophe theory to transient stability assessment of multi-machine power system [PDF]

open access: yes, 2013
Transient stability analysis is an important part of power planning and operation. For large power systems, such analysis is very demanding in computation time. On-line transient stability assessment will be necessary for secure and reliable operation of
Bugis, Ismadi, Hassen Kareem, Maithem
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Dual generator cluster transient stability assessment using swallowtail catastrophe theory

open access: yes, 2013
In this paper swallowtail catastrophe is used to determine the transient stability regions. The bifurcation set represents the transient stability region in terms of power system transient parameters bounded by the transient stability limits.
Bugis, Ismadi, Hassen Kareem, Maithem
core  

Probabilistic transient stability assessment for on-line applications

open access: yesInternational Journal of Electrical Power & Energy Systems, 2012
Abstract The increasing need to improve security monitoring of networks by system operators is the main motivation of the work described in this paper. The paper provides an algorithm for the on-line probabilistic transient stability assessment of existing or forecasted operating conditions.
Mehdi Abapour, Mahmoud-Reza Haghifam
openaire   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Comparison of three power system software packages for small-signal stability analysis

open access: yes, 2009
Includes bibliographical references (leaves 131-133).Many power system simulation tools exist for small-signal stability analysis. This is due to the rapid development of computer systems, higher industrial growth and the need for reliable power system ...
Mudau, Dovhani Selby
core  

Intelligent Enhanced Method for Modern Power System Transient Voltage Stability Assessment Based on Improved Conditional Generative Adversarial Network

open access: yesEnergies
The increasing complexity and variability of operating conditions, along with the occurrence of low-probability cascading failures, imposes more stringent requirements on data-driven intelligent methods for power system stability analysis.
Fan Li   +5 more
doaj   +1 more source

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