Results 61 to 70 of about 93,389 (292)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A Transient Stability Assessment Method using Post-Fault Trajectories [PDF]

, 2013
Transient Stability Assessment (TSA) is the process in which the stability of a system is characterized qualitatively or quantitatively. The TSA algorithm presented in this paper is derived from the well-established Single Machine Equivalent (SIME ...
Kyriakidis, Theodoros, Kayal, Maher, Guillaume Lanz, Rachid Cherkaoui, Cherkaoui, Rachid, Maher Kayal, Lanz, Guillaume, Theodoros Kyriakidis   +7 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Direct Transient Stability Assessment Of Stressed Power Systems

, 2014
{"references": ["P. Kundur, Power system Stability and Control. The ERPI Power system\nEngineering Series, 1994, pp. 17.", "V. Jalili-Marandi, \"Instantaneous relaxation-based real-time transient\nStability Simulation,\" IEEE Trans. Power Systems, vol. 24, no. 3,\npp.1327-1336, Aug.
E. Popov, N. Yorino, Y. Zoka, Y. Sasaki, H. Sugihara   +4 more
openaire   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The impact of wind generators on a Powe system's transient stability

, 2009
This thesis discusses the investigations carried out on the different types of wind generators and how these would affect the transient stability of a hypothetical power network as presented in this report.
Khomari, Moloantoa
core  

Power System Transient Stability Assessment Based on Snapshot Ensemble LSTM Network

, 2021
Data-driven methods using synchrophasor measurements have a broad application prospect in Transient Stability Assessment (TSA). Most previous studies only focused on predicting whether the power system is stable or not after disturbance, which lacked a ...
Zhijian Hu, Yixing Du
core   +1 more source

Transient Stability Analysis Method of Power System Based on Multi-source Data Drive

Taiyuan Ligong Daxue xuebao
Purposes At present, the data driven method represented by deep learning has been widely used in power transient stability analysis. However, the existing transient stability models for researching data driving have some problems, such as limited ...
Ying QU, Xiaoqing HAN, Xinyuan LIU, Xiaohui LU, Tao MENG, Ying ZHANG   +5 more
doaj   +1 more source