Results 81 to 90 of about 271,893 (300)

An Overabundance of Transient X-ray Binaries within 1 pc of the Galactic Center

, 2004
During five years of Chandra observations, we have identified seven X-ray transients located within 23 pc of Sgr A*. These sources each vary in luminosity by more than a factor of 10, and have peak X-ray luminosities greater than 5e33 erg/s, which ...
A. Ghez, E. Pfahl, F. K. Baganoff, J. Lu, King A. R., Lee H. M., M. P. Muno, M. R. Morris, Verbunt F., W. N. Brandt, Wegner W.   +10 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

All Transients, All the Time: Real-Time Radio Transient Detection with Interferometric Closure Quantities

, 2012
We demonstrate a new technique for detecting radio transients based on interferometric closure quantities. The technique uses the bispectrum, the product of visibilities around a closed-loop of baselines of an interferometer.
Baars, Booth, Briggs, Casey J. Law, Clark, Condon, Cornwell, Geoffrey C. Bower, Hallinan, Hallinan, Law, Lazio, Lomnicki, Macquart, Macquart, McLaughlin, Parsons, Perley, Pfahl, Siemion, Wharton   +20 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Research of controlled switching strategy to restrain inrush current during the energisation of converter transformer

The Journal of Engineering, 2019
When an unloaded converter transformer is being energised, large inrush current may flow in the voltage jump side depending upon the residual flux in the core and the closing voltage angle of the power grid due to the hysteresis characteristics of the ...
Duo Wang, Zhiguo Hao, Zijia Hui, Ke Wang, Guocheng Ding   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Transient global amnesia mimics: Transient epileptic amnesia

Epilepsy & Behavior Case Reports, 2014
We describe the case of a 79-year-old patient referred for suspected transient global amnesia, after an episode of anterograde amnesia which lasted 90 min. An EEG, performed after the episode, showed bilateral temporal electrographic seizures, orienting the diagnosis toward a transient epileptic amnesia.
Nicastro, Nicolas, Picard, Fabienne, Assal, Frederic   +2 more
openaire   +4 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Noise-induced stabilization of saddle-node ghosts

New Journal of Physics, 2020
It is known that saddle-node (s-n) bifurcations leave a saddle remnant (or ghost) in the region of the phase space where the annihilation of the fixed points occurred.
Josep Sardanyés, Carles Raich, Tomás Alarcón   +2 more
doaj   +1 more source