Results 81 to 90 of about 8,637 (288)

For Them but Never Really Theirs: Finding a Place for the “Aged” Within State-Funded Institutions in Nineteenth-Century Nova Scotia [PDF]

, 2009
This paper reveals that between 1867 and the 1890s, care for the aged within state funded institutions in Nova Scotia underwent several important changes that reflected the intentions of the province to avoid long term responsibility for the needy.
DesRoches, Cheryl
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The spread of infectious diseases in migration routes between caravans and resident communities: Modelling yellow fever in Central America

The Journal of Climate Change and Health
Introduction: Climate-sensitive diseases are significantly affected by weather patterns and the social consequences of a changing climate. In this context, epidemics and human mobility can interact, leading to unpredictable impacts on both human and ...
Sabrina Soares Simon, Marcos Amaku, Eduardo Massad   +2 more
doaj   +1 more source

Living with Change Among a Transient Population: <i>Narratives and Practices of Collective Belonging among Swedish Migrants on the Costa del Sol in Spain¹</i>

Nordic Journal of Migration Research, 2017
The article explores how the Swedish migrants narrate and practice collective belonging as strategies to handle life in a region characterised by a transient and circulating population on the Costa del Sol, Spain. It is based on an ethnographic research within the Swedish infrastructure of organizations, institutions, and private enterprises, in ...
openaire   +1 more source

LGUs Need Strong National Leadership in Population Management [PDF]

Can LGUs succeed in managing their own population? They probably can, but they need strong national leadership in doing so. This Policy Notes asserts that population management is a national rather than a local issue.
Orbeta, Aniceto Jr. C.
core  

Re-education through labour in historical perspective [PDF]

, 2005
Re-education through labour (laodong jiaoyang or laojiao for short) is an administrative punishment imposed by the police. Since its inception in 1955, it has become a convenient instrument for the government to use to deal with any crisis.
Hualing, F
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Reducing loneliness among migrant and ethnic minority people: a participatory evidence synthesis

Public Health Research, 2020
Background: To date, there has been little research into the causes of, and solutions to, loneliness among migrant and ethnic minority people. Objectives: The objectives were to synthesise available evidence and produce new insights relating to ...
Sarah Salway, Elizabeth Such, Louise Preston, Andrew Booth, Maria Zubair, Christina Victor, Raghu Raghavan   +6 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Birds of the North Gulf Coast - Prince William Sound Region, Alaska [PDF]

, 1973
The North Gulf Coast - Prince William Sound region of Alaska, phytographically, lies at the northern limit of the Sitka Spruce-hemlock coastal/subalpine forests of the Pacific Coast; it includes approximately 178,500 km2 and a shoreline of approximately ...
Isleib, M. E., Kessel, Brina
core