Results 51 to 60 of about 2,228,086 (285)

Towards a Sustainable i-City: Intelligent Transition Management of Digital Places

open access: yesKvalita Inovácia Prosperita, 2017
Modern cities operate in a force field of great challenges. The introduction of digital technology may facilitate the necessary transition management of cities but calls also for a new and intelligent use of a wealth of information for coping with great
Karima Kourtit
doaj   +1 more source

Market Imperfections within the European Wheat Value Chain: The Case of France and the United Kingdom

open access: yesAgriculture, 2021
The focus of this paper is on the analysis of market imperfections in the French and U.K. wheat value chains. We used mark-up and mark-down models and stochastic frontier analysis to estimate the degree of market imperfections in two completely different
Lukáš Čechura   +1 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Revealing the Determinants of Wheat Yields in the Siberian Breadbasket of Russia with Bayesian Networks [PDF]

open access: yesProstranstvennaâ Èkonomika, 2019
Higher crop yields are critical to satisfy the rising global food demand. Russia holds untapped potential for increasing agricultural production because current grain yields are often far below the potentially attainable yields.
Alexander V. Prishchepov   +3 more
doaj   +1 more source

Self-induced topological transition in phononic crystals by nonlinearity management

open access: yes, 2019
A new design paradigm of topology has recently emerged to manipulate the flow of phonons. At its heart lies a topological transition to a nontrivial state with exotic properties. This framework has been limited to linear lattice dynamics so far.
Chaunsali, Rajesh, Theocharis, Georgios
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Holistic Approach to Niche Formation: A Case on Transition to Nearly Zero-Energy Buildings in Türkiye

open access: yesBuildings
The long-term challenges of climate change are becoming increasingly evident. Considering the ever-increasing need for energy in parallel with population growth and the impact of greenhouse gases, the built environment is among the issues that should be ...
Tuğba Yiğit Barut   +1 more
doaj   +1 more source

Habitual accountability routines in the boardroom: How boards balance control and collaboration [PDF]

open access: yes, 2017
open3siCorporate accountability is a complex chain of reporting that reaches from external stakeholders into the organization’s management structure.
Amedeo Pugliese   +3 more
core   +3 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

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