Results 71 to 80 of about 229,475 (313)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Mapping the Twilight Zone—What We Are Missing between Clouds and Aerosols

open access: yesRemote Sensing, 2017
Scientific understanding of aerosol-cloud interactions can profit from an analysis of the transition regions between pure aerosol and pure clouds as detected in satellite data.
Katharina Schwarz   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Transition to Chaos in the Floating Half Zone Convection

open access: yes, 2007
The transition process from steady convection to chaos is experimentally studied in thermocapillary convections of floating half zone. The onset of temperature oscillations in the liquid bridge of floating half zone and further transitions of the ...
阿燕   +3 more
core  

(Table 3) Chemical composition of tuffs, basalts, and mineral inclusions from the transition zone of the Reykjanes Ridge

open access: yes, 1997
(Table 3) Chemical composition of tuffs, basalts, and mineral inclusions from the transition zone of the Reykjanes ...
Gennady S Kharin (6959660)   +1 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction

open access: yesAnnals of Medicine
Objective To evaluate the longitudinal changes in the effective optical zone (EOZ) following hyperopic keratorefractive lenticule extraction (KLEx) and investigate factors influencing the EOZ.Patients and methods This retrospective study included 27 ...
Yangyi Huang   +5 more
doaj   +1 more source

One-dimensional physical reference models for the upper mantle and transition zone: combining seismic and mineral physics constraints

open access: yes
One-dimensional seismic reference models are known to be a nonunique solution to global seismic data, hampering an interpretation in terms of physical structure. Here we test the compatibility of the simplest hypothesis of a mantle convecting as a whole,
Giardini, D.   +3 more
core   +1 more source

Role of Transition Zone Index in the Prediction of Clinical Benign Prostatic Hyperplasia

open access: yes, 2016
Objective The objective of this study was to determine the role of the transition zone (TZ) index (TZI) in the prediction of clinical benign prostatic hyperplasia (BPH) in patients who underwent transurethral prostatectomy (TUR-P) and to analyze the ...
Muhammet Güzelsoy, Ziya Kirkali
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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