Results 51 to 60 of about 28,818 (311)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Absolute configurations of 1,10-phenanthroline and 2,2′-bipyridine metal complexes

, 1969
The nonempirical circular dichroism method for determining the distribution of chelate rings in dissymmetric metal complexes, which is based on long-axis-polarized π → π ligand transitions, is reviewed and applied to some cobalt(III), chromium (III), and
Ferguson, J., Hawkins, C. J., Lip, H., Kane-Maguire, N. A.P.   +3 more
core   +1 more source

Assessment of TD-DFT and LF-DFT for study of d - d transitions in first row transition metal hexaaqua complexes [PDF]

, 2015
Herein, we present the systematic, comparative computational study of the d - d transitions in a series of first row transition metal hexaaqua complexes, [M(H2O)(6)](n+) (M2+/3+ = V2+/3+, Cr2+/3+, Mn2+/3+, Fe2+/3+, Co2+/3+, Ni2+) by the means of Time ...
Vlahović, Filip, Zlatar, Matija, Perić, Marko, Gruden-Pavlović, Maja, Marko Perić, Filip Vlahović, Matija Zlatar, Maja Gruden-Pavlović   +7 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Photochemistry of transition metal p-benzoquinone complexes

, 2014
Complexes of Pd(II), Rh(I) and Ir(I) with p-quinone ligands are characterized by metal or ligand (iodide,azide) to quinone CT transitions. CT excitation yields hydroquinones as reduction products. (C) 2014 Elsevier B.V.
Vogler, Arnd
core   +1 more source

Synthesis and Optical Characterization of Mixed Ligands Beryllium Complexes for Display Device Applications

International Journal of Optics, 2015
Synthesis and photoluminescent behaviour of mixed ligand based beryllium complexes with 2-(2-hydroxyphenyl)benzoxazole (HPB) and 5-chloro-8-hydroxyquinoline (Clq) or 5,7-dichloro-8-hydroxyquinoline (Cl2q) or 2-methyl-8-hydroxyquinoline (Meq) or 8 ...
Vandna Nishal, Devender Singh, Raman Kumar Saini, Vijeta Tanwar, Shri Bhagwan, Sonika Kadyan, Ishwar Singh, Pratap Singh Kadyan   +7 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Luminescent heteroleptic copper(I) complexes with polydentate benzotriazolyl-based ligands [PDF]

, 2021
Bis(benzotriazol-1-yl)phenylmethane CHPh(btz)2 and tris(benzotriazol-1-yl)methane CH(btz)3 were used as N-donor ligands to prepare luminescent heteroleptic copper(I) complexes.
Bortoluzzi, Marco, Agostinis, Lodovico, Castro, Jesús, Ferraro, Valentina   +3 more
core   +1 more source

Electronic and photophysical properties of copper (II) Complexes: Insights into solvatochromic Effects, Photoreduction, and fluorescence behavior

Results in Chemistry
This study delves into the intricate electronic and photophysical properties of copper (II) complexes and their ligands, shedding light on their behavior under varying conditions.
Haja Tar, Lama M. Alhomaidan, Lotfi Beji, Abrar S. Alnafisah, Noura Kouki, Sabri Messaoudi, Fahad M. Alminderej, Azizah A. Algreiby, Lotfi M. Aroua   +8 more
doaj   +1 more source

Co[MeCycHexdtc]2 AND Co[EtCycHexdtc]2: SYNTHESIS, CHARACTERIZATION AND CORROSION INHIBITION SCREENING IN HCl AND H2SO4

Journal of Academia, 2021
Most industries used acids during the cleaning process where they may cause a severe corrosion attack to the metal surface. Corrosion inhibitor was utilized to reduce the corrosion rate.
Mimi Wahidah Mohd Radzi, Nur Alia Atiqah Alias, Fasihah Esa   +2 more
doaj