Results 81 to 90 of about 31,514 (264)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Parallels Between Goffman’s Interaction Order and Interpreting Interaction in Community Interpreting

İstanbul Üniversitesi Çeviribilim Dergisi
The aim of this paper is to descriptively show to what extent the interaction sociological approach of the interaction order, developed by the American sociologist Erving Goffman, has points of contact with interpreter interaction in community ...
Yelda Arkan
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Community Interpreting Training in Türkiye: A Study Based on the Views of Academics and Interpreters

İstanbul Üniversitesi Çeviribilim Dergisi
Health tourism along with cultural tourism, educational opportunities, natural disasters, and recent conflicts in the region have made community interpreting an indispensable service in Türkiye. This rise in the sector should also, in correlation, affect
Gizem Yaren Kutlu, Aslı Özlem Tarakçıoğlu   +1 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Training refugees to become interpreters for refugees

Translation and Interpreting : the International Journal of Translation and Interpreting Research, 2010
RMIT University, Translating and Interpreting Program in partnership with the Victorian Multicultural Commission (VMC, formerly Victorian Office of Multicultural Affairs or VOMA), has been offering a National Australian Authority for Translators and ...
Miranda Lai, Sedat Mulayim
doaj  

Child Language Brokering Among Migrant/Refugee Communities in Türkiye

İstanbul Üniversitesi Çeviribilim Dergisi
Children who most quickly assimilate the language and social and cultural norms of the host country in a family carry out interpreting tasks for their families in different contexts shortly after migration.
Özge Bayraktar Özer
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

The Position of Localization Literature (1998-2024) in Türkiye

İstanbul Üniversitesi Çeviribilim Dergisi
Localization is a (sub-)field within Translation Studies via the efforts of agents of localization who invest their capital and time in specializing within localization.
Dilruba Temuçin, Mehmet Cem Odacıoğlu, Atalay Gündüz   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source