Results 81 to 90 of about 33,668 (304)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Certificate Translation in Abstract Interpretation [PDF]

open access: yes, 2008
A certificate is a mathematical object that can be used to establish that a piece of mobile code satisfies some security policy. Since in general certificates cannot be generated automatically, there is an interest in developing methods to reuse certificates.
Gilles Barthe, César Kunz
openaire   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

خارطة العمليات العقلية الخاصة بالترجمة الفورية

open access: yesTraduction et Langues, 2018
The Mental Process in Simultaneous Interpreting Simultaneous interpreting is one of the most difficult tasks. It requires great intellectual and psychological efforts.
Houaria Chaal
doaj  

Valero-Garcés, Carmen (2014). Communicating Across Cultures. A Coursebook on Interpreting and Translating in Public Services and Institutions [PDF]

open access: yes, 2015
Valero-Garcés, Carmen (2014). Communicating Across Cultures. A Coursebook on Interpreting and Translating in Public Services and Institutions. Lanham/Plymouth: University Press of America Inc., pp. 207, €23.91.
GENTILE, PAOLA
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Translating and Interpreting George Orwell in Ukraine: A Study of Literary and Critical Engagement

open access: yesAmerican and British Studies Annual
This article explores the different ways George Orwell’s works have entered Ukrainian culture, with a particular focus on the translations that have introduced his sharp political commentary to Ukrainian readers. Apart from translations, we will examine
Iryna Malyshivska, David Livingstone
doaj   +1 more source

Translators and interpreters, translation and interpretation

open access: yes, 2013
Discussion of the processes of communication in Southeast Asia, in the 16th-18th centuries, between the Portuguese seafarers and the local population, mainly traders and political rulers. Central is the role of the interpreters, as intermediaries ad as translators not just of language but also of customs and etiquette. In addition, the special position
openaire   +2 more sources

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