Results 91 to 100 of about 1,773,214 (315)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Translation of Sounds for Children: an Example of a Multimodal Work

open access: yes, 2023
Translation of poetry, particularly intended for children, has always been considered as one of the most problematic and challenging sub-fields of literary translation.
Hastürkoğlu, Gökçen   +1 more
core  

Delivering the National Diabetes Prevention Program: Assessment of Retention, Physical Activity, and Weight Loss Outcomes by Participant Characteristics and Delivery Modes

open access: yesJournal of Diabetes Research
Type 2 diabetes disproportionately affects older adults, persons from racial and ethnic minority groups, and persons of low socioeconomic status. It can be prevented or delayed through evidence-based interventions such as the National Diabetes Prevention
Boon Peng Ng   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Comparing rule-based and data-driven approaches to Spanish-to-Basque machine translation [PDF]

open access: yes, 2007
In this paper, we compare the rule-based and data-driven approaches in the context of Spanish-to-Basque Machine Translation. The rule-based system we consider has been developed specifically for Spanish-to-Basque machine translation, and is tuned to ...
Stroppa, Nicolas   +3 more
core  

To Translate or not to Translate? [PDF]

open access: yesMeta: Journal des traducteurs, 1985
A partir d'exemples sur les difficultes de la traduction tirees de la litterature et en particulier de la poesie («les correspondances» de Baudelaire), est recense l'ensemble des problemes, souvent incontournables que pose la langue a un traducteur charge de trouver d'une langue a une autre un concept ...
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Translation of a book of evidence and its impact on a criminal trial - A case study [PDF]

open access: yes, 2012
Interpreting in a legal setting in Ireland is not subject to any regulation. Police and court interpreters are neither certified nor tested. The current study aims to analyse the impact on a criminal trial of unqualified interpreters’ assistance in the ...
Jarmolowska, Karolina
core  

Community translation

open access: yes, 2022
Community translation facilitates communication between national and local public services, on the one hand, and speakers of non-official or minority languages on the other.
Taibi, Mustapha (R12032)
core  

The effectiveness of guideline implementation strategies in the dental setting: a systematic review

open access: yesImplementation Science, 2019
Background Guideline implementation has been an ongoing challenge in the dental practice setting. Despite this, there are no reviews summarising the existing evidence regarding effective guideline implementation strategies in this setting.
Amy R. Villarosa   +5 more
doaj   +1 more source

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