Results 91 to 100 of about 5,276,450 (332)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Evaluative reports on medical malpractice policies in obstetrics: a rapid scoping review
Systematic Reviews, 2017 Background The clinical specialty of obstetrics is under particular scrutiny with increasing litigation costs and unnecessary tests and procedures done in attempts to prevent litigation.
Roberta Cardoso +11 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Dublin City University at CLEF 2007: Cross-Language Speech Retrieval Experiments [PDF]
, 2008 The Dublin City University participation in the CLEF 2007 CL-SR English task concentrated primarily on issues of topic translation. Our retrieval system used the BM25F model and pseudo relevance feedback.
Jones, Gareth J.F. +2 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Humanities & Social Sciences CommunicationsThis bibliometric study aims to analyze the translated literature in the Arab nations that exhibit the highest levels of dynamism spanning from 1979–2012, using the Index Translationum database.
Fawziah Ali Alshehri +4 more
doaj +1 more source
Stem Cell Research & Therapy, 2020 Background Graft-versus-host disease (GvHD) is the main life-threatening complication of allogeneic hematopoietic stem cell transplantation (HSCT). Thirty to 80% of GvHD patients do not respond to first-line treatment and a second-line treatment is not ...
Cynthia Morata-Tarifa +3 more
doaj +1 more source
Literary translation and cultural memory [PDF]
, 2008 This article intends to investigate the relationship between literary translation and cultural memory, using a twentieth century film version of one of Shakespeare’s plays as a case study in inter-semiotic translation.
Long, Lynne
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source