Results 111 to 120 of about 1,773,214 (315)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Factors impacting long-term care and retirement home populations’ participation in immunity research: a qualitative study using the framework method

BMC Geriatrics
Background The COVID-19 pandemic had a severe impact on Long-Term Care Homes (LTCH) and Retirement Homes (RH) in Canada. Urgent research was required to understand characteristics of COVID-19 transmission and immunity among this at-risk population, yet ...
Christine Fahim, Vanja Grubac, Temi Odunuga, Larkin Davenport-Huyer, Taehoon Lee, Jamie M. Boyd, Sharon E. Straus   +6 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

The way we do things matters: the deep integration of lived experience in the a/part of the crowd project to respond to loneliness in young adults

Research Involvement and Engagement
Background Loneliness in youth (15–24 years old) is increasing. The impacts over the life course are more fully recognised and require co-designed responses.
Candice Peart, Matthew Lewis, Jennifer Bibb, Grace Read, Kisanet Tesfu, Kushagra Rathore, Li Xuan Tan, Toby Wong, Alison Turner, Farhan Andalib, Gianna Ziero, Jemma Rule, Lidan Cao, Lyam Merritt, Nargis Rezaie, Tyesha Shelton, Cath Kaylor-Hughes, Amy Coe, Phillip Orcher Muruwori/Gumbaynggirr, Victoria J. Palmer   +19 more
doaj   +1 more source

Intrinsic managing and the English-Arabic translation of fictional registers

Cogent Arts & Humanities
The translation process involves several changes made to the source text. Some of these changes, referred to as intrinsic managing , are necessary to overcome linguistic differences and create a cohesive, coherent, and natural text without altering the ...
Hadeel Saed, Ahmad S. Haider, Sausan Abu Tair, Eisa Asiri   +3 more
doaj   +1 more source

Translation as a Process and Translation as a Product in Teaching Translation

Sintagma, 2003
L'ensenyament de la traducció s'ha utilitzat tradicionalment en algunes titulacions de filologia com a eina d'aprenentatge d'habilitats de la llengua. Aquesta circumstància, però, no ha d'estar renyida amb la producció d'una traducció acceptable. En aquest article es pretén analitzar si pot aconseguir-se aquest objectiu mitjançant la incorporació d ...
openaire   +3 more sources

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

MATEO : MAchine Translation Evaluation Online

, 2023
We present MAchine Translation Evaluation Online (MATEO), a project that aims to facilitate machine translation (MT) evaluation by means of an easy-to-use web interface that can evaluate given machine translations with a battery of automatic metrics.
Vanroy, BramUGent0001615296528020026585439747705382060000-0002-4622-8364C50B0474-7EE0-11E7-B38D-2BA4AD28A064, Popovic, Majaeditor, Brenner, Juditheditor, Nurminen, Maryeditor, Mikhailov, Mikhaileditor, Forcada, Mikeleditor, Alvarez Vidal, Sergieditor, Scarton, Carolinaeditor, Ranasinghe, Tharindueditor, Koponen, Maariteditor, Aranberri, Noraeditor, Parra Escartín, Carlaeditor, Latomaa, Sirkkueditor, Nunziatini, Maraeditor, Tezcan, ArdaLW220020058519838020017673550000-0002-8707-6176E4E9C51C-9502-11E3-A4F6-4F4B11BDE39D, Macken, LieveLW228020002457680000-0001-7516-7487F93DB0F6-F0ED-11E1-A9DE-61C894A0A6B4, Vanmassenhove, Evaeditor, Schierl, Frederikeeditor, Moniz, Helenaeditor   +18 more
core  

The neglected association between schizophrenia and bone fragility: a systematic review and meta-analyses

Translational Psychiatry
Schizophrenia is associated with increased risk of medical comorbidity, possibly including osteoporosis, which is a public health concern due to its significant social and health consequences.
Behnaz Azimi Manavi, Kayla B. Corney, Mohammadreza Mohebbi, Shae E. Quirk, Amanda L. Stuart, Julie A. Pasco, Jason M. Hodge, Michael Berk, Lana J. Williams   +8 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source