Results 101 to 110 of about 5,227,080 (312)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Multilingual search for cultural heritage archives via combining multiple translation resources [PDF]
The linguistic features of material in Cultural Heritage (CH) archives may be in various languages requiring a facility for effective multilingual search.
Debole, Franca +4 more
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
This study explores the representation of women in Arabic and English literature by female writers and examines whether this representation carries into translated works. First, it analyzes the linguistic choices female writers make to portray women
Manal Abdulkareem Mohammed +1 more
doaj +1 more source
The Abbasid translation movement in context : contemporary voices on translation [PDF]
Over the decades, an enormous amount of scholarly work has been devoted to the historical and literary context of the Greek-Arabic translations. Without it, we would not be able to answer vital questions about dating and translators.
Vagelpohl, Uwe
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Based on the cross-sectional data about the municipal Party committee secretaries sacked since the 18th CPC National Congress, this paper adopts a regression model to examine and assess the impact of local top Party leaders’ corruption.
Liao Chongxu, Li Huoqiang, Zhou Dong
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Background Little is known about disparities in access to preventive care among people of multiple races, who are often aggregated into a single category, despite comprising a heterogeneous population. We therefore described the prevalence of barriers to
Alain K. Koyama +7 more
doaj +1 more source

