Results 131 to 140 of about 5,388,665 (365)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Intrinsic managing and the English-Arabic translation of fictional registers
Cogent Arts & HumanitiesThe translation process involves several changes made to the source text. Some of these changes, referred to as intrinsic managing , are necessary to overcome linguistic differences and create a cohesive, coherent, and natural text without altering the ...
Hadeel Saed +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Translating the Diabetes Prevention Program Into an Urban Medically Underserved Community [PDF]
, 2008 Miriam Seidel +4 more
openalex +1 more source
Subcytoplasmic location of translation controls protein output
, 2023 Ellen L. Horste +8 more
openalex +1 more source
Findings of the 2019 Conference on Machine Translation (WMT19) [PDF]
, 2019 This paper presents the results of the premier shared task organized alongside the Conference on Machine Translation (WMT) 2019. Participants were asked to build machine translation systems for any of 18 language pairs, to be evaluated on a test set of ...
Barrault, Loïc +5 more
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Translatome profiling: methods for genome-scale analysis of mRNA translation [PDF]
, 2014 Helen King, André P. Gerber
openalex +1 more source