Results 11 to 20 of about 2,935,766 (379)
Hijacking Translation Initiation for Synthetic Biology
ChemBioChem, 2020 Genetic code expansion (GCE) has revolutionized the field of protein chemistry. Over the past several decades more than 150 different noncanonical amino acids (ncAAs) have been co‐translationally installed into proteins within various host organisms. The
Jeffery M. Tharp +3 more
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Functional Translational Readthrough: A Systems Biology Perspective.
PLoS Genetics, 2016 Translational readthrough (TR) has come into renewed focus because systems biology approaches have identified the first human genes undergoing functional translational readthrough (FTR).
Fabian Schueren, Sven Thoms
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Metabolic influences on RNA biology and translation [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2017 Protein translation is one of the most energetically demanding processes for a cell to undertake. Changes in the nutrient environment may result in conditions that cannot support the rates of translation required for cell proliferation. As such, a cell must monitor its metabolic state to determine which mRNAs to translate into protein.
Chien-Der Lee, Benjamin P. Tu
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Repurposing the translation apparatus for synthetic biology. [PDF]
Current Opinion in Chemical Biology, 2015 The translation system (the ribosome and associated factors) is the cell's factory for protein synthesis. The extraordinary catalytic capacity of the protein synthesis machinery has driven extensive efforts to harness it for novel functions. For example, pioneering efforts have demonstrated that it is possible to genetically encode more than the 20 ...
B. D. Soye +3 more
semanticscholar +4 more sources
Translational synthetic biology [PDF]
Systems and Synthetic Biology, 2015 Synthetic biology is a recent scientific approach towards engineering biological systems from both pre-existing and novel parts. The aim is to introduce computational aided design approach in biology leading to rapid delivery of useful applications. Though the term reprogramming has been frequently used in the synthetic biology community, currently the
Mamta Singh, Anuradha Vaidya
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Found in translation: Understanding the biology and behavior of experimental traumatic brain injury [PDF]
Neuroscience and Biobehavioral Reviews, 2014 Corina O. Bondi +7 more
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Antibody cocktail effective against variants of SARS-CoV-2
Journal of Biomedical Science, 2021 Background Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus with a high mutation rate.
Kang-Hao Liang +10 more
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Heliyon, 2023 The COVID-19 pandemic continues to threaten human health worldwide as new variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerge. Currently, the predominant circulating strains around the world are Omicron variants, which can
Ruei-Min Lu +11 more
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How to eat an idea-A roadmap for translation and impact in plant biology. [PDF]
Plant PhysiolNapier JA.
europepmc +2 more sources
Nonsense-mediated mRNA decay factor UPF1 promotes aggresome formation
Nature Communications, 2020 Nonsense-mediated mRNA decay (NMD) is a translation-coupled process that eliminates mRNAs containing premature translation-termination codons. Here the authors identify a role for the NMD factor UPF1 in protein quality control, whereby truncated ...
Yeonkyoung Park +7 more
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