Beyond Arabidopsis. Translational Biology Meets Evolutionary Developmental Biology [PDF]
Abstract Developmental processes shape plant morphologies, which constitute important adaptive traits selected for during evolution. Identifying the genes that act in developmental pathways and determining how they are modified during evolution is the focus of the field of evolutionary developmental biology, or evo-devo.
Vivian F, Irish, Philip N, Benfey
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eIF2B-capturing viral protein NSs suppresses the integrated stress response
Here the authors show that a viral protein interferes with the binding of phosphorylated eIF2 to eIF2B, thereby suppressing the host integrated stress response (ISR). This suppression of the ISR abrogates translational changes of the host and ameliorates
Kazuhiro Kashiwagi +10 more
doaj +1 more source
The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans [PDF]
Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA-Argonaute complex-or miRNA-induced silencing complex (miRISC)-can regulate the translation of their targets in such diverse ways.
Bajan, Sarah +7 more
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Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]
Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K +7 more
core +2 more sources
Imaging Atherosclerotic Plaque Calcification: Translating Biology [PDF]
Calcification of atherosclerotic lesions was long thought to be an age - related, passive process, but increasingly data has revealed that atherosclerotic calcification is a more active process, involving complex signaling pathways and bone-like genetic programs.
Grant, Bailey +2 more
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The emerging role of RNA modifications in the regulation of mRNA stability
Gene activity: the significance of RNA modification Messenger RNA molecules play their key role in directing the manufacture of proteins via translating the genetic information in DNA.
Sung Ho Boo, Yoon Ki Kim
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Novel capsid binder and PI4KIIIbeta inhibitors for EV-A71 replication inhibition
The Hand, Foot and Mouth Disease (HFMD) is a highly contagious viral illness generally manifests as a mild disease in young children and immunocompromised adults.
Yong Wah Tan +5 more
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The novel coronavirus disease (COVID-19) pandemic remains a global public health crisis, presenting a broad range of challenges. To help address some of the main problems, the scientific community has designed vaccines, diagnostic tools and therapeutics ...
Monika Kumari +16 more
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Problems of specialist translations on examples of texts from domains like biology, biotechnology and medicine [PDF]
This article deals with the analysis of problems in translation of EU directives from English into Polish. The examples were taken from three directives regulating medicine, biology and biotechnology-related matters.
Kłos, Patrycja +2 more
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YAMAT-seq: an efficient method for high-throughput sequencing of mature transfer RNAs. [PDF]
Besides translation, transfer RNAs (tRNAs) play many non-canonical roles in various biological pathways and exhibit highly variable expression profiles.
Honda, Shozo +5 more
core +2 more sources

