Results 71 to 80 of about 8,994,214 (249)

Routledge Research on Translation and Interpreting History

open access: yes
Routledge Research on Translation and Interpreting History showcases cutting-edge research in English on the interdisciplinary dialogue between translation and interpreting studies and historical perspectives.
Rundle Christopher
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Time Matters: Conceptual and Methodological Considerations in Translation Timescapes

open access: yesChronotopos, 2019
Time is a fundamental concept and context in translation history that merits more specific consideration than it has generally been accorded by translation scholars.
Judy Wakabayashi
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Guy de Maupassanti novellid Eestis XX sajandi algupoolel. Tõlked ja retseptsioon läbi dekadentsi prisma

open access: yesKeel ja Kirjandus
In the early 20th century, the influx of foreign literary movements into Estonia was largely facilitated through print media. Periodicals predominantly favoured concise and captivating stories.
Kaia Sisask
doaj   +1 more source

MAPPING TRANSLATION HISTORY IN IRAN: A SCIENTOMETRIC STUDY OF JOURNAL ARTICLES [PDF]

open access: yesEnglish Studies at NBU
This study presents a scientometric analysis of scholarly publications on the history of translation in Iran, encompassing 370 articles published over a fifty-year period. Using VOSviewer for data visualization, the research identifies and maps eight key
Fatemeh Parham
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

České překlady Jesenina a sovětská ideologie

open access: yesActa Universitatis Carolinae Philologica, 2019
Dealing with a so far unknown part of Czech translation history, the paper uncovers traces of communist ideology in Czech translations of poems written by a Russian and Soviet poet Sergey Jesenin (1895–1925). First, it focuses on the Jesenin translations
Stanislav Rubáš
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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