Results 71 to 80 of about 1,605,540 (300)
A Complementary Mechanism of Bacterial mRNA Translation Inhibition by Tetracyclines
Frontiers in Microbiology, 2021 Tetracycline has positively impacted human health as well as the farming and animal industries. Its extensive usage and versatility led to the spread of resistance mechanisms followed by the development of new variants of the antibiotic.
Victor Barrenechea +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
wiley +1 more source
Previously published repeat length-independent translation initiation sites.
, 2022 Previously published repeat length-independent translation initiation sites.
Yoshifumi Sonobe (217333) +4 more
core +1 more source
Comprehensive profiling of translation initiation in influenza virus infected cells.
PLoS Pathogens, 2019 Translation can initiate at alternate, non-canonical start codons in response to stressful stimuli in mammalian cells. Recent studies suggest that viral infection and anti-viral responses alter sites of translation initiation, and in some cases, lead to ...
Heather M Machkovech +2 more
doaj +1 more source
Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF-κB.
PLoS ONE, 2013 Protein synthesis is mainly regulated at the initiation step, allowing the fast, reversible and spatial control of gene expression. Initiation of protein synthesis requires at least 13 translation initiation factors to assemble the 80S ribosomal ...
Giuseppe Fiume +13 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
A Deeper Look into Translation Initiation [PDF]
Cell, 2014 Eukaryotic translation initiation requires coordinated assembly of a remarkable array of initiation factors onto the small ribosomal subunit to select an appropriate mRNA start codon. Studies from Erzberger et al. and Hussain et al. bring new insights into this mechanism by looking at early and late initiation intermediates.
openaire +3 more sources
The Role of Translation Initiation Regulation in Haematopoiesis [PDF]
Comparative and Functional Genomics, 2012 Organisation of RNAs into functional subgroups that are translated in response to extrinsic and intrinsic factors underlines a relatively unexplored gene expression modulation that drives cell fate in the same manner as regulation of the transcriptome by transcription factors.
Godfrey Grech, Marieke von Lindern
openaire +3 more sources
Tumor suppression by small molecule inhibitors of translation initiation [PDF]
, 2012 Translation initiation factors are over-expressed and/or activated in many human cancers and may contribute to their genesis and/or progression. Removal of physiologic restraints on translation initiation causes malignant transformation.
Denoyelle, Severine +14 more
core +1 more source
eLifeTranslation initiation in eukaryotes requires a 40 S ribosome loaded with initiator tRNA which scans for an initiation codon. The initiator tRNA is usually recruited to the ribosome as part of a ternary complex composed of initiator tRNA, eIF2, and GTP ...
Mykola Roiuk +2 more
doaj +1 more source