Results 181 to 190 of about 23,501 (259)

Mechanically Regulated Secretion: How Physical Forces Instruct the Secretory Pathway and Remodel the Secretome

Advanced Science, EarlyView.
Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo, Seetharaman Parashuraman, Maria Luigia Maresca, Angela Francesca Dinoi, Alessia Calcagnì, Riccardo Rizzo   +5 more
wiley   +1 more source

Impact of incorrect affiliations on the recognition of Mexican scientific institutions. [PDF]

Rev Med Inst Mex Seguro Soc
Gradilla-Magaña P, Cisneros-Barrios A, Barajas-Ochoa A, Castañeda-Delgado JE, Ramos-Remus C.   +4 more
europepmc   +1 more source

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

Advanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim, Jiwon Lee, Minjeong Kang, Sung Sun Yim, Donghui Choe, Byung‐Kwan Cho   +5 more
wiley   +1 more source

A gene set collection of human RBP target genes. [PDF]

Sci Data
Glaß M, Hüttelmaier S.
europepmc   +1 more source

3D Bioprinted Blood–Brain–Tumor Barrier Spheroid‐Based In Situ Evaluation of Anticancer Compounds Against Glioblastoma: ROS‐Producing Ruthenium as a Potential Therapeutic Candidate

Advanced Science, EarlyView.
The blood–brain–tumor barrier (BBTB) penetration by anticancer drugs and their effects on glioblastoma (GBM) is assessed using 3D bioprinted‐spheroids. Anticancer drug‐induced U‐87 MG cell death is quantified through in situ imaging of spheroids using a cancer cell death probe. The Ru compound, a partial P‐gp substrate, induces greater tumor‐cell death
Hyunjung Lee, Chan Ho Jeon, Doyun Kim, Minjae Lee, Minji Kwon, Joon Myong Song   +5 more
wiley   +1 more source

The Complex Biology of EIF3E (int6): From Its Original Discovery to <i>EIF3E::RSPO2</i> Fusions in Solid Tumors and Lymphoma Susceptibility. [PDF]

Cancers (Basel)
Marchetti A, Buttitta F.
europepmc   +1 more source

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source

A Matter of Font: Visual Word Form Area Responses to Brand Names Are More Sensitive to Font Than to Letter Case Changes. [PDF]

Neurobiol Lang (Camb)
Labusch M, Perea M, Davydova T, Pérez MB, Melle CC, Rodriguez EV, Zaragoza ER, Costumero V.   +7 more
europepmc   +1 more source

Multi‐Target Wireless Localization of Miniaturized Magneto–Oscillatory Trackers in Soft Biological Tissues

Advanced Science, EarlyView.
Miniaturized, frequency‐encoded magneto–oscillatory trackers enable wireless localization of multiple targets without prior knowledge of their positions or orientations. The method achieves accurate localization over clinically relevant distances and measures local viscoelasticity via the oscillatory responses.
Liyuan Tan, Jyothi Kumari Mariyanna, Meng Zhang, Alexander Kutscher, Ann‐Sophia Müller, Felix Fischer, Tian Qiu   +6 more
wiley   +1 more source

Extensive Proteomic Approach to Assess Protein Alterations in Human Hepatoma Huh7 Cells Infected with West Nile Virus. [PDF]

Int J Mol Sci
Shaba E, Landi C, Vicenti I, Vantaggiato L, Saladini F, Biba C, Bartolini N, Zazzi M, Bini L.   +8 more
europepmc   +1 more source