Results 41 to 50 of about 29,113 (284)

4-(Adamantan-1-yl)-2-(4-fluorophenyl)quinoline

Acta Crystallographica Section E, 2013
In the molecule of the title compound, C25H24FN, the dihedral angle between the best planes of the quinoline fragment (rings A and B) and the benzene ring (C) is 9.51 (4)°.
Zuzana Kozubková, Eva Babjaková, Peter Bartoš, Robert Vícha   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Challenges of translating C. S. Lewis’s “The Problem of Pain” into Polish and Spanish by professional translators – comparative and evaluative perspectives [PDF]

Studia Translatorica
The article discusses diverse translation challenges which translators may be confronted with while working on target-language renditions of C. S. Lewis’s “The Problem of Pain”. To present his thoughts and theses, this famous British writer, philosopher,
Adam Palka
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Numerical semigroups bounded by the translation of a plane monoid [PDF]

, 2021
M. A. Moreno-Frías, J. C. Rosales
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Meaning does not have to be rendered in words: Intersemiotic translation in digital religious infographics

Indonesian Journal of Applied Linguistics
Data visualization is becoming widespread nowadays as people grasp images faster than verbal information. Infographics delineate information visually to be easily intelligible to the audience. They are creative discursive spaces where complex information
Mai Mowafy
doaj   +1 more source

Comparison of Roll and Pitch Among Patients with Vertical and Horizontal Skeletal Patterns Using Cant-O-Meter: A New Gyroscopic Device for Measuring Occlusal Cant

Journal of Indian Orthodontic Society, 2022
In Orthodontics, initial classification of malocclusions was based on planar malocclusions in the anteroposterior, transverse and vertical planes that were based only on translation of the jaws in space.
Janani Ravi, Poornima Jnaneshwar, R. Krishnaraj, K. Ravi   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source