Results 41 to 50 of about 28,389 (247)

2-{(E)-N-[2-(1H-Inden-3-yl)ethyl]iminomethyl}-1H-imidazole

Acta Crystallographica Section E, 2011
The asymmetric unit of the title compound, C15H15N3, contains two crystallographically independent molecules with very similar geometries. The imidazole and indenyl planes are approximately orthogonal, making dihedral angles of 88.21 (9) and 83.
Zhao Li, Chong Tian, Wanli Nie, Maxim V. Borzov   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Poly[[tri-μ-cyanido-cyanido(1,4,10,13-tetraoxa-7,16-diazacyclooctadecane)barium(II)platinum(II)] hemihydrate]

Acta Crystallographica Section E, 2009
The title compound, {[BaPt(CN)4(C12H26N2O4)]·0.5H2O}n, is a two-dimensional coordination polymer in which the sheets are oriented approximately parallel to the (overline{1}01) set of crystal planes.
Marilyn M. Olmstead, Christine M. Beavers, Latisha Paw U   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Sagittal instability with inversion is important to evaluate after syndesmosis injury and repair: a cadaveric robotic study

Journal of Experimental Orthopaedics, 2020
Purpose Disruption of the syndesmosis, the anterior-inferior tibiofibular ligament (AITFL), the posterior-inferior tibiofibular ligament (PITFL), and the interosseous membrane (IOM), leads to residual symptoms after an ankle injury. The objective of this
Neel K. Patel, Conor I. Murphy, Thomas R. Pfeiffer, Jan-Hendrik Naendrup, Jason P. Zlotnicki, Richard E. Debski, MaCalus V. Hogan, Volker Musahl   +7 more
doaj   +1 more source

Six degree-of-freedom knee joint kinematics in obese individuals with knee pain during gait. [PDF]

PLoS ONE, 2017
Knee joint pain is a common symptom in obese individuals and walking is often prescribed as part of management programs. Past studies in obese individuals have focused on standing alignment and kinematics in the sagittal and coronal planes. Investigation
Jing-Sheng Li, Tsung-Yuan Tsai, David T Felson, Guoan Li, Cara L Lewis   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Stable elastic nail application with poller K-wire for Irreducible distal radius metaphyseal-diaphyseal Junction fractures in preadolescents: a new operative technique

BMC Musculoskeletal Disorders
Background Surgical treatment of irreducible distal radius diaphyseal- metaphyseal junction fractures involves difficulties as the fracture remains too proximal for K-wire fixation and too distal for the elastic stable intramedullary nail. Our study aims
Levent Horoz, Mehmet Fevzi Cakmak, Cihan Kircil   +2 more
doaj   +1 more source

5-Benzylidene-3-phenyl-2-phenylimino-1,3-thiazolidin-4-one

Acta Crystallographica Section E, 2011
The title compound, C22H16N2OS, is a chalcone analog with a thiazolidinone core that was synthesized as a potential cytotoxic and anticancer agent. The structure is commensurately modulated by unit-cell doubling along the direction of the a axis of the ...
Matthias Zeller, Vijay Satam, Ravi Kumar Bandi, Ajaya Kumar Behera, Bijay Kumar Mishra, Hari Pati, Moses Lee   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source