Results 91 to 100 of about 1,056,460 (305)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

The Comparison of Translation Strategies in the Old and New Translations of The 100: A Ranking of the Most Influential People in History by Michael Hart

Journal of Language and Literature
Translations of the same text might be different from one version to another based on the translation strategies that are used by the translator. By examining the translation strategies in the old and the new translations of a book titled The 100: A ...
Ananda Nayla, Haru Deliana Dewi
doaj   +1 more source

TRANSLATION PROCEDURES OF CULTURE BOUND WORDS USED IN VISITOR GUIDE OF JAWA TENGAH [PDF]

, 2015
This thesis is entitled Translation Procedures of Culture Bound Words Used in Visitor Guide of Jawa Tengah. Some of procedures used in the translation of this book dealing with non-equivalence at word level and the culture word and here in describe any ...
WIDARA, NARASWARI SIWI
core  

Translation Procedure of English to Indonesian Subtitle 'English Vinglish' Movie

Rainbow: Journal of Literature, Linguistics and Culture, 2020
The objectives of this research are to find the types and the most dominant type of translation procedures of English into Indonesian Subtitle in “English Vinglish” Movie. This research is descriptive qualitative research.
Tira Nur Fitria
doaj   +1 more source

TRANSLATING LEGAL TEXTS: COMPONENTIAL ANALYSIS AS A TRANSLATION PROCEDURE

Lingua Montenegrina, 2010
Author deals with the issue of translating texts from the field of criminal law from English to Montenegrin and vice-versa. The focus is on English and Montenegrin lexis from the area of criminal procedure law. The main aim is to establish translation equivalents of relevant lexical items from this field, as well as to ...
openaire   +1 more source

Trio-One: Layering Uncertainty and Lineage on a Conventional DBMS [PDF]

, 2007
Trio is a new kind of database system that supports data, uncertainty, and lineage in a fully integrated manner. The first Trio prototype, dubbed Trio-One, is built on top of a conventional DBMS using data and query translation techniques together with a
Agrawal, P., Benjelloun, O., Das Sarma, A., Keijzer, A. de, Murthy, R., Mutsuzaki, M., Sugihara, T., Theobald, M., Widom, J.   +8 more
core   +5 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source