Results 71 to 80 of about 1,056,460 (305)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Problems of translation of Orthodox non-equivalent lexis to English

Kamasean
Cultural elements and systems often do not match up between two cultures which use different languages, which represents one of the main problems in the domain of translation.
Ivana Knežević, Zoran Ranković
doaj   +1 more source

THE ANALYSIS OF TRANSLATION PROCEDURES IN TWILIGHT SAGA NEW MOON THE MOVIE [PDF]

, 2015
Dedeh Hilda M. : THE ANALYSIS OF TRANSLATION PROCEDURES IN “TWILIGHT SAGA; NEW MOON” THE MOVIE This study aims to identify and analyze the translation procedures applied by translators in translating texts Twilight Saga; New Moon movie subtitles ...
DEDEH HILDA MUJAHIDAH,
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

EXACT2: the semantics of biomedical protocols [PDF]

, 2014
© 2014 Soldatova et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
A Maccagnan, A Pease, A Sackmann, A Sujathaa, Brian B Rudkin, CJ Mungall, Daniel Nadis, Doi, Emma Haddi, Grunwald, H Obokata, I Mura, J Taubert, K Wolstencroft, Larisa N Soldatova, LN Soldatova, LN Soldatova, LN Soldatova, M Courtot, M Hilario, M Schilling, Nigel J Saunders, Piyali S Basu, R Garside, RD King, Ross D King, RR Brinkman, S Mitchell, S Rune, S Shapin, T Bittner, T Klingström, Th Paul, V Rätzel, Véronique Baumlé, W Ceusters, Wolfgang Marwan, Z Xiang   +37 more
core   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Translation Procedures in Translating Proper Names from English into Indonesian

Humanis, 2020
Translation procedure is a procedure or a method to translate the unit of language from the source language to the target language. Every linguistic part needs to be translated. It means including the proper names in the literary work. This study is aimed at identifying and analyzing the types of the proper name and their translation procedures in the ...
Ni Putu Devi Lestari, I Made Winaya, I Gst. Ayu Gede Sosiowati   +2 more
openaire   +3 more sources

AN ANALYSIS OF TRANSLATION PROCEDURES OF MEDICAL TERMS IN A MEDICAL TEXTBOOK ENTITLED “INTRODUCTION TO HUMAN PHYSIOLOGY” BY LAURALEE SHERWOOD [PDF]

, 2014
This study analyzed translation procedures of medical terms in a medical textbook entitled “Introduction to Human Physiology” by Lauralee Sherwood. The specific purposes of this study were to find out noun phrase structures in medical terms, translation ...
Eristianingrum, Ysahi Tantias
core