Results 61 to 70 of about 46,251,330 (370)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
Is preclinical research in cancer biology reproducible enough?
eLife, 2021 The Reproducibility Project: Cancer Biology (RPCB) was established to provide evidence about reproducibility in basic and preclinical cancer research, and to identify the factors that influence reproducibility more generally.
Patrick Bodilly Kane, Jonathan Kimmelman
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib
eLife, 2015 Poor study methodology leads to biased measurement of treatment effects in preclinical research. We used available sunitinib preclinical studies to evaluate relationships between study design and experimental tumor volume effect sizes.
Valerie C Henderson +6 more
doaj +1 more source
Humanities & Social Sciences Communications, 2022 Among modern Chinese female writers and translators, Bing Xin is considered an elite pioneer and leader of the May Fourth/New Culture Movement. Through a sentimental and feminist writing style, she showcases her own voice and distinctive features.
Zhinan Ji, Meng Xiangchun
doaj +1 more source
Second language learning: finding ways to successfully integrate ICT resources and right strategies for language learning, translation and interpreting [PDF]
, 2019 Second language learning: finding ways to integrate ICT resources and right strategies for language learning, translation and interpreting Second language learning has gained importance as language accreditations have become imperative for any ...
Pérez Carrasco, Míriam
core
Zhang Yimou's 'Blood simple':cannibalism, remaking and translation in world cinema [PDF]
, 2014 Zhang Yimou’s A Woman, A Gun and A Noodle Shop (2009) remakes the Coen brothers’ Blood Simple (1984) in a way that re-imagines the earlier film in a Chinese setting, adapting and recreating the narrative, but the film cannot be regarded as being aimed ...
Evans, Jonathan
core +2 more sources
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Discriminative Region Proposal Adversarial Networks for High-Quality Image-to-Image Translation
, 2018 Image-to-image translation has been made much progress with embracing Generative Adversarial Networks (GANs). However, it's still very challenging for translation tasks that require high quality, especially at high-resolution and photorealism.
C Dong +9 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source