Results 51 to 60 of about 341,454 (248)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Prasasti: Journal of LinguisticsGame subtitle must be translated using proper techniques to avoid misunderstanding when the game is played. In addition, Indonesian and English have different systems of personal pronouns, which must be known and understood by the translator.
Haura Nabila Rinaldi, Doni Jaya
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
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ELT Forum: Journal of English Language Teaching, 2013 This final project was a study which analyzed the use of translation techniques in the bilingual textbook BIOLOGY 1for Senior High School Year X Published by Yudhistira. The study was done qualitatively.
Ikma Qurrota A'yun
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TRANSLATION TECHNIQUE IN TRANSLATING INDONESIAN FABELS INTO ENGLISH
Lingua Scientia, 2021 This paper aims to describe translation techniques used in translating Indonesian Fables into English. The data is taken from bilingual fable books from five different publishers. The research uses purposive sampling technique and also comparative method to analyze the data.
Usep Muttaqin +2 more
openaire +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Applied SciencesThe exploitation and development of photovoltaic (PV) modules faces several technical challenges, including those related to variability in electrical performance under real conditions, such as temperature fluctuations, irradiance variability, and dust ...
Lawan Sani +4 more
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
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