Results 71 to 80 of about 6,415,224 (301)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Translator’s Techniques in Translating Military Acronyms

open access: yesالمجلة العربية للعلوم الإنسانية والاجتماعية
This research paper delves into the intricate realm of translating military acronyms from English to Arabic, shedding light on the techniques employed by translators to navigate the complexities of this specialized field. With the growing importance of cross-cultural communication in military contexts, the accurate translation of acronyms plays a
null عمر قصي علي الشوبكي   +1 more
openaire   +1 more source

Anthology of Arabic Discourse on Translation

open access: yes, 2021
This anthology brings the key writings on translation in Arabic in the pre-modern era, extending from the earliest times (sixth century CE) until the end of World War I, to a global English-speaking audience.

core   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

The Concept of Equivalence and Translation Techniques in the Poststructuralists’ Theories of Translation

open access: yesRespectus Philologicus, 2015
This article studies the development of the translation theories in the second half of the twentieth century, a period during which significant theoretical contributions were made in translation circles. These contributions had a profound impact on the practice of translation.
openaire   +4 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Combining multi-domain statistical machine translation models using automatic classifiers [PDF]

open access: yes, 2010
This paper presents a set of experiments on Domain Adaptation of Statistical Machine Translation systems. The experiments focus on Chinese-English and two domain-specific corpora. The paper presents a novel approach for combining multiple domain-trained
Li, Baoli   +5 more
core   +2 more sources

Translating culture: Translation strategies and techniques for Proverbs [PDF]

open access: yes
This research work aims to analyze the translation strategies and techniques used in translating English proverbs about friendship into Kazakh, with a special focus on their cultural and linguistic adaptation.
Islamova, A.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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