Results 51 to 60 of about 1,345,360 (299)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Visually Impaired Novice Translators in Using Translation Techniques

Script Journal: Journal of Linguistics and English Teaching, 2021
Background: This study aims to determine the translation techniques used by visually impaired translators in translating popular scientific texts. Visually impaired translators were used as the subjects of this study because when compared to sighted translators, visually impaired translators had a different way of doing translation activities.
Raden Arief Nugroho, Muljono Muljono, Mangatur Rudolf Nababan   +2 more
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Hand in hand: automatic sign Language to English translation [PDF]

, 2007
In this paper, we describe the first data-driven automatic sign-language-to- speech translation system. While both sign language (SL) recognition and translation techniques exist, both use an intermediate notation system not directly intelligible for ...
Dreuw, Philippe, Morrissey, Sara, Ney, Hermann, Stein, Daniel, Way, Andy   +4 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Experiments on domain adaptation for English-Hindi SMT [PDF]

, 2009
Statistical Machine Translation (SMT) systems are usually trained on large amounts of bilingual text and monolingual target language text. If a significant amount of out-of-domain data is added to the training data, the quality of translation can drop ...
Haque, Rejwanul, Naskar, Sudip Kumar, van Genabith, Josef, Way, Andy   +3 more
core   +1 more source

A Positivity Theorem for Gravitational Tension in Brane Spacetimes

, 2003
We study transverse asymptotically flat spacetimes without horizons that arise from brane matter sources. We assume that asymptotically there is a spatial translation Killing vector that is tangent to the brane.
Gibbons G W, Gubser S S, Jennie Traschen, Regge T, Townsend P K, Traschen J Fox D, Witten E   +6 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Keakuratan Terjemahan Gaya Bahasa pada Novel Lady Chatterley’s Lover

Ranah: Jurnal Kajian Bahasa, 2018
Translating accuracy of source language into target language in a literary work require high appropriatness that retain the beauty of the language. The purpose of this study is to identify and describe level of accuracy of the translation in the figure ...
Nidya Pratiwi, M.R Nababan, NFN Djatmika
doaj   +1 more source

TMX markup: a challenge when adapting SMT to the localisation environment [PDF]

, 2010
Translation memory (TM) plays an important role in localisation workflows and is used as an efficient and fundamental tool to carry out translation. In recent years, statistical machine translation (SMT) techniques have been rapidly developed, and the ...
Du, Jinhua, Roturier, Johann, Way, Andy
core