Results 81 to 90 of about 498,490 (353)

The online computer-assisted translation classroom

open access: yesTranslation and Interpreting : the International Journal of Translation and Interpreting Research, 2020
In the modern translation industry, all actors involved in the translation process communicate and collaborate increasingly – and oftentimes entirely – online using modern computer-assisted translation and project management software solutions.New ...
Viktorija Bilic
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Quantifying the Effect of Machine Translation in a High-Quality Human Translation Production Process

open access: yesInformatics, 2020
This paper studies the impact of machine translation (MT) on the translation workflow at the Directorate-General for Translation (DGT), focusing on two language pairs and two MT paradigms: English-into-French with statistical MT and English-into-Finnish ...
Lieve Macken, Daniel Prou, Arda Tezcan
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Wrapper syntax for example-based machine translation [PDF]

open access: yes, 2006
TransBooster is a wrapper technology designed to improve the performance of wide-coverage machine translation systems. Using linguistically motivated syntactic information, it automatically decomposes source language sentences into shorter and ...
Mellebeek, Bart   +4 more
core  

Multiword units in machine translation and translation technology

open access: yes, 2018
The correct interpretation of Multiword Units (MWUs) is crucial to many applications in Natural Language Processing but is a challenging and complex task.
Johanna Monti   +11 more
core   +1 more source

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