Results 31 to 40 of about 40,351 (275)

Politeness in Ecuadorian Spanish [PDF]

open access: yes, 1996
This paper examines politeness phenomena in Ecuadorian Spanish as reflected in the language of telephone conversations, and, as such, attempts to add another cultural perspective to the discussion of politeness issues and of Brown and Levinson's (1978 ...
Placencia, Maria Elena
core   +1 more source

The universality of poetry in Aristotle’s Poetics [PDF]

open access: yes, 1991
This paper considers three questions arising out of Aristotle's statement that poetry is concerned with the universal. First, what does it mean? Secondly, what constraints does it impose on the construction of (in particular) tragic plots?
Belfiore   +15 more
core   +1 more source

Manifest Quasi-Universals and Embedding Conceptual Clusters

open access: yesAsian Studies, 2022
We start this article with a discussion of the problematics involved in translating into modern English a (modern) Chinese text concerning a classical Chinese notion, namely qíng 情. Then, we suggest that it is necessary to distinguish between two levels
Jaap van Brakel, Lin Ma
doaj   +1 more source

Universally conserved translation initiation factors

open access: yesProceedings of the National Academy of Sciences, 1998
The process by which translation is initiated has long been considered similar in Bacteria and Eukarya but accomplished by a different unrelated set of factors in the two cases. This not only implies separate evolutionary histories for the two but also implies that at the universal ancestor stage, a translation initiation mechanism either ...
N C, Kyrpides, C R, Woese
openaire   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Implicitation in Legal Translation - A Study of Spanish-Danish Translation of Judgments

open access: yesHermes, 2016
Whilst the concept of explicitation has spawned many research projects in the field of Translation Studies, implicitation remains an understudied area.
Anja Krogsgaard Vesterager
doaj   +1 more source

Truth­-Makers [PDF]

open access: yes, 2008
During the realist revival in the early years of this century, philosophers of various persuasions were concerned to investigate the ontology of truth. That is, whether or not they viewed truth as a correspondence, they were interested in the extent to ...
Mulligan, Kevin   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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