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Translation, Translation, Translation [PDF]
Three factors dominate the calculation of real estate value: location, location, and location. As I enter the second half of my editorship of Circulation Research , my reflections pinpoint translation, translation, and translation as the three critical factors dominating the future of our journal.
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In modern linguistics, one of the current topics is the study of the relationships between languages, as one of the main means of transmission of meanings and the socio-cultural reality. Among the many challenges studied by the modern linguistics, an important place is the study of the linguistic aspects of cross-language speech activity, which is ...
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Elongation factor P (EF-P) is a ubiquitous translation factor that facilitates translation of polyproline motifs. In order to perform this function, EF-P generally requires posttranslational modification (PTM) on a conserved residue.
Anne Witzky +6 more
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In recent years, preclinical pain research has failed to develop genuinely new analgesics for clinical use. This fact is reflected by a high number of patients, limited drug efficacy accompanied by side effects, and a long-term opioid intake.
Daniel Segelcke +5 more
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The majority of colorectal cancers (CRCs) are microsatellite stable (MSS) and resistant to immunotherapy. The current study explores the possibility of using oncolytic reovirus to sensitize MSS CRC to immune checkpoint inhibition.
Titto Augustine +18 more
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Assessment of Antifungal Pharmacodynamics
Pharmacokinetic-pharmacodynamic (PK-PD) analysis is of central importance to the progress of an antifungal agent into clinical use. It is crucial to ensure that preclinical studies give the best possible prediction of the way drugs are likely to behave ...
Alex Howard, William Hope
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Translational research in neuroanaesthesia
Translational research in anaesthesia provided great solutions to medicine, well beyond its scope, in the past. Exciting opportunities exist for neuroanaesthesiologists to conduct translational research not just in anaesthesia alone but in the wider ...
Ganne S. Umamaheswara Rao
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The role of PACAP/PAC1R in PTSD: effects on fear extinction via the ventromedial hypothalamus
Introduction The incidence and severity of posttraumatic stress disorder (PTSD) is higher in women than men because of environmental and biological factors.
R. Andero
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The Modified Canine Groove Model of Osteoarthritis
Background/Objectives: In the original canine groove model of osteoarthritis (OA), superficial scratches to the cartilage lead to slow progressive cartilage damage, with inflammation mimicking key aspects of human disease.
Goran S. van der Weiden +6 more
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Indian communities have the ancient cultural practice of gentle oil massage for infants which has been shown to play a beneficial role in neuro-motor development.
Aditi Apte +6 more
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