Results 201 to 210 of about 1,480,919 (260)

Diabetic cardiomyopathy as a disorder of proteostatic maladaptation: context-dependent ubiquitin-specific protease networks. [PDF]

Front Cell Dev Biol
Meng X, Guo S, Lin H, Li R, Peng W, Sun L, Shi X, Yang L.   +7 more
europepmc   +1 more source

Near‐Infrared Imaging of H2O2 in Plants With Nanosensors Under Environmentally Changing Conditions

Advanced Materials, EarlyView.
This paper reports a ratiometric nanosensor enabling robust, multivariate detection of stress signals (H2O2) in plants, with high resistance to light fluctuations and mechanical disturbances. Single‐walled carbon nanotubes serve as the sensor, Egyptian Blue nanosheets serve as a stable reference, and plant autofluorescence serves as a label‐free ...
Jiaqi Li, Bjoern F. Hill, Chen Ma, Juliana Gretz, Tanuja Kistwal, Janus A. C. Wartmann, Justus T. Metternich, Juan Pablo Giraldo, Sebastian Kruss   +8 more
wiley   +1 more source

Deciphering the Redox-Mediated Interplay Along the Gut-Lung-Brain Axis: Macrophage and Microglia Hyperactivation in Systemic Inflammation. [PDF]

Antioxidants (Basel)
Park SJ, Lee HJ, Lee SU, Lee JW.
europepmc   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Motion Anisotropy of Individual, Unconfined Rod-Like-Shaped <i>Salmonella</i> Typhimurium Bacteria. [PDF]

ACS Nanosci Au
Diestelhorst K, Ghazisaeedi F, Klimek A, Braetz S, Tedin K, Netz RR, Fulde M, Block S.   +7 more
europepmc   +1 more source

A Noninvasive Approach to Study Localized Forces in 3D Epithelia

Advanced Materials, EarlyView.
Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand, Muhamet Ibrahimi, Claire Valotteau, Brice Lecouffe, André Le Bivic, Dominique Massey‐Harroche, Felix Rico, Matthias Merkel, Delphine Delacour, Elsa Bazellières   +9 more
wiley   +1 more source

Development and Preliminary Technical Validation of an Interactive, Surgeon-Oriented Framework for Digital Surgical Occlusion Planning in Orthognathic Surgery. [PDF]

J Clin Med
Gugliotta Y, Olivetti EC, Bruno G, Galasso GM, Roccia F, Ferretti F, Moos S, Vezzetti E, Marcolin F, Ramieri G.   +9 more
europepmc   +1 more source

Plasmonically Enhanced Microarray Immunoassay for High‐Sensitivity Monitoring of Heart Failure

Advanced Materials, EarlyView.
A novel plasmonically enhanced PE‐D4 assay combines nanopatch antennas with a microarray immunoassay for the detection of heart failure biomarkers NT‐proBNP, NGAL, and galectin‐3 in complex biological samples. Plasmonic amplification substantially enhances fluorescence signals, enabling sensitive biomarker quantification with a low‐cost smartphone ...
Daria Semeniak, Deniz Acil, Jason Liu, Daniela F. Cruz, Cassio M. Fontes, Chengyang Li, Brooke E. Silverstein, G. Michael Felker, Angus M. Hucknall, Maiken H. Mikkelsen, Ashutosh Chilkoti   +10 more
wiley   +1 more source

Bioinspired Adaptive Artificial Cilia With Tunable Sensitivity and Dynamic Range for Airflow Monitoring in the Central Airway

Advanced Materials Technologies, EarlyView.
A magnetically reconfigurable airflow sensor integrated with an airway stent enables tunable sensitivity and dynamic sensing range. Airflow‐induced cantilever deformation generates resistance changes, while an external magnetic field modulates sensor stiffness, enhancing sensitivity at low airflow velocities and extending the sensing range at higher ...
Darren Wang, Ruijian Ge, Shuda Dong, Zhongming Lyu, Yusheng Wang, Nicholas Strymish, Hanwen Fan, Fabien Maldonado, Caitlin T. Demarest, Yuxiao Zhou, Xiaoguang Dong   +10 more
wiley   +1 more source