Results 31 to 40 of about 409,300 (260)

Using bibliometrics to evaluate outcomes and influence of translational biomedical research centers

open access: yesJournal of Clinical and Translational Science, 2022
Introduction: Federal grant funding to support infrastructure development of translational biomedical research centers is a form of public health intervention.
Kristine M. Bragg   +3 more
doaj   +1 more source

Digital microarrays: single-molecule readout with interferometric detection of plasmonic nanorod labels [PDF]

open access: yes, 2018
DNA and protein microarrays are a high-throughput technology that allow the simultaneous quantification of tens of thousands of different biomolecular species.
Daaboul, George G.   +4 more
core   +1 more source

Investigación traslacional en el currículo de medicina: una propuesta de reforma desde la práctica docente. Reflexiones sobre la reforma curricular

open access: yesEducación Médica
Resumen: La medicina o investigación traslacional es una nueva rama de la medicina, que promueve el desarrollo científico a partir de la estrecha relación entre la investigación básica, preclínica y clínica, lo cual ha generado importantes avances en la ...
Manuel Latorre Quintana   +2 more
doaj   +1 more source

The Value of Comparative Animal Research : Krogh’s Principle Facilitates Scientific Discoveries [PDF]

open access: yes, 2017
There are no conflicts of interest to declare. This paper developed from the 2016 Early Career Impact Award from the Federation of Associations in Behavioral & Brain Sciences to TJS. TJS has received funding from The Leverhulme Trust.
Alward, Beau A.   +5 more
core   +2 more sources

Translational Research: An Imperative Shaping the Spaces in Biomedicine

open access: yesTecnoscienza, 2014
In this paper we recapitulate the history of the conceptual entwinement of biomedicine and translation and argue that a translational imperative (still peripheral to the practices that order the fields unified under the term biomedicine) has come to ...
Jean Harrington, Christine Hauskeller
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Biomedical Informatics Applications for Precision Management of Neurodegenerative Diseases [PDF]

open access: yes, 2018
Modern medicine is in the midst of a revolution driven by “big data,” rapidly advancing computing power, and broader integration of technology into healthcare. Highly detailed and individualized profiles of both health and disease states are now possible,
Jimenez-Maggoria, Gustavo   +3 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Computational Models for Transplant Biomarker Discovery. [PDF]

open access: yes, 2015
Translational medicine offers a rich promise for improved diagnostics and drug discovery for biomedical research in the field of transplantation, where continued unmet diagnostic and therapeutic needs persist.
Sarwal, Minnie M, Wang, Anyou
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

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