Collaborative software for traditional and translational research
Human Genomics, 2012 Biomedical research has entered a period of renewed vigor with the introduction and rapid development of genomic technologies and next-generation sequencing methods.
Berman Ari E +2 more
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The Value of Comparative Animal Research : Krogh’s Principle Facilitates Scientific Discoveries [PDF]
, 2017 There are no conflicts of interest to declare. This paper developed from the 2016 Early Career Impact Award from the Federation of Associations in Behavioral & Brain Sciences to TJS. TJS has received funding from The Leverhulme Trust.
Alward, Beau A. +5 more
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MODERN APPROACHES TO THE ORGANIZATION OF TRANSLATIONAL RESEARCH
Педиатрическая фармакология, 2014 The growing distance between fundamental science and clinical medicine may bring risk of decreasing effectiveness of biomedical research. Translational research is a relatively new concept; it implies application of fundamental research results to ...
A. S. Kolbin +2 more
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Translational medicine and the NIHR Biomedical Research Centre concept [PDF]
QJM, 2008 The realization of scientific discovery being delivered to patients for their clinical benefit is termed Translational Medicine. This requires the bridging of excellence in both basic scientific endeavour and clinical care. Whilst there is consensus that it is important to drive translation for the benefit of patient care, the mechanism whereby this is
Snape, K., Trembath, R. C., Lord, G. M.
openaire +3 more sources
Translational Research: An Imperative Shaping the Spaces in Biomedicine
Tecnoscienza, 2014 In this paper we recapitulate the history of the conceptual entwinement of biomedicine and translation and argue that a translational imperative (still peripheral to the practices that order the fields unified under the term biomedicine) has come to ...
Jean Harrington, Christine Hauskeller
doaj +1 more source
Using bibliometrics to evaluate outcomes and influence of translational biomedical research centers
Journal of Clinical and Translational Science, 2022 Introduction: Federal grant funding to support infrastructure development of translational biomedical research centers is a form of public health intervention.
Kristine M. Bragg +3 more
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Improving communication skill training in patient centered medical practice for enhancing rational use of laboratory tests: The core of bioinformation for leveraging stakeholder engagement in regulatory science. [PDF]
, 2013 Requests for laboratory tests are among the most relevant additional tools used by physicians as part of patient's health problemsolving. However, the overestimation of complementary investigation may be linked to less reflective medical practice as a ...
Chiappelli, Francesco +5 more
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Poor Translatability of Biomedical Research Using Animals — A Narrative Review
Alternatives to Laboratory Animals, 2023 The failure rate for the translation of drugs from animal testing to human treatments remains at over 92%, where it has been for the past few decades. The majority of these failures are due to unexpected toxicity — that is, safety issues revealed in human trials that were not apparent in animal tests — or lack of efficacy.
Lindsay J. Marshall +4 more
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Educación MédicaResumen: La medicina o investigación traslacional es una nueva rama de la medicina, que promueve el desarrollo científico a partir de la estrecha relación entre la investigación básica, preclínica y clínica, lo cual ha generado importantes avances en la ...
Manuel Latorre Quintana +2 more
doaj +1 more source
A novel closed-chest porcine model of chronic ischemic heart failure suitable for experimental research in cardiovascular disease [PDF]
, 2013 Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF).
Antonio Amodeo +15 more
core +3 more sources