Results 41 to 50 of about 687,731 (280)

Selection-driven cost-efficiency optimization of transcripts modulates gene evolutionary rate in bacteria

open access: yesGenome Biology, 2018
Background Most amino acids are encoded by multiple synonymous codons. However, synonymous codons are not used equally, and this biased codon use varies between different organisms.
Emily A. Seward, Steven Kelly
doaj   +1 more source

Genome-wide analysis of codon usage bias in four sequenced cotton species. [PDF]

open access: yesPLoS ONE, 2018
Codon usage bias (CUB) is an important evolutionary feature in a genome which provides important information for studying organism evolution, gene function and exogenous gene expression.
Liyuan Wang   +9 more
doaj   +1 more source

Discovery of indole-modified aptamers for highly specific recognition of protein glycoforms

open access: yesNature Communications, 2021
Glycosylation is an abundant form of post-translational modification. Here the authors present a generalizable workflow for the selection of indole-modified aptamers that can recognize protein glycoforms with high specificity.
Alex M. Yoshikawa   +10 more
doaj   +1 more source

Attempted use of PACE for riboswitch discovery generates three new translational theophylline riboswitch side products

open access: yesBMC Research Notes, 2018
Objective The purpose of this project was to use an in vivo method to discover riboswitches that are activated by new ligands. We employed phage-assisted continuous evolution (PACE) to evolve new riboswitches in vivo.
Zachary M. Shaver   +30 more
doaj   +1 more source

Internal Transitions of Two-Dimensional Charged Magneto-Excitons X-: Theory and Experiment

open access: yes, 1999
Internal spin-singlet and spin-triplet transitions of charged excitons X- in magnetic fields in quantum wells have been studied experimentally and theoretically.
A. Petrou   +18 more
core   +1 more source

Object Manipulation in Virtual Reality Under Increasing Levels of Translational Gain [PDF]

open access: yes, 2018
Room-scale Virtual Reality (VR) has become an affordable consumer reality, with applications ranging from entertainment to productivity. However, the limited physical space available for room-scale VR in the typical home or office environment poses a ...
Ajoy   +12 more
core   +2 more sources

Variation and selection on codon usage bias across an entire subphylum.

open access: yesPLoS Genetics, 2019
Variation in synonymous codon usage is abundant across multiple levels of organization: between codons of an amino acid, between genes in a genome, and between genomes of different species.
Abigail L LaBella   +4 more
doaj   +1 more source

Selection for Translational Efficiency in Genes Associated with Alphaproteobacterial Gene Transfer Agents

open access: yesmSystems, 2022
Gene transfer agents (GTAs) are virus-like elements that are encoded by some bacterial and archaeal genomes. The production of GTAs can be induced by carbon depletion and results in host lysis and the release of virus-like particles that contain mostly ...
Roman Kogay, Olga Zhaxybayeva
doaj   +1 more source

Rayleigh-Benard Convection in Large-Aspect-Ratio Domains

open access: yes, 2004
The coarsening and wavenumber selection of striped states growing from random initial conditions are studied in a non-relaxational, spatially extended, and far-from-equilibrium system by performing large-scale numerical simulations of Rayleigh-B\'{e}nard
I. Catton   +5 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

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