Results 21 to 30 of about 3,061,365 (279)
Frontiers in Cellular and Infection Microbiology, 2018 Live attenuated vaccines are widely used to protect humans or animals from pathogen infections. We have previously developed a chicken embryo-attenuated Duck Hepatitis A Virus genotype 1 (DHAV-1) vaccine (CH60 strain).
Xumin Ou +48 more
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UMCCTS Newsletter, August 2022 [PDF]
, 2022 This is the August 2022 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through Grant
UMass Center for Clinical and Translational Science
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Analysis of factors shaping synonymous codon usage in pseudorabies virus
浙江大学学报. 农业与生命科学版, 2007 Synonymous codon usage and the main factors shaping codon usage in pseudorabies virus were reported in order to understand the architecture and evolution of pseudorabies virus.
YIN Hua-ping +3 more
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Estimating Translational Selection in Eukaryotic Genomes [PDF]
Molecular Biology and Evolution, 2008 Natural selection on codon usage is a pervasive force that acts on a large variety of prokaryotic and eukaryotic genomes. Despite this, obtaining reliable estimates of selection on codon usage has proved complicated, perhaps due to the fact that the selection coefficients involved are very small.
dos Reis, M, Wernisch, L
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Viruses, 2013 Viral codon usage bias may be the product of a number of synergistic or antagonistic factors, including genomic nucleotide composition, translational selection, genomic architecture, and mutational or repair biases.
Siobain Duffy +2 more
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Fine-Tuning Translation Kinetics Selection as the Driving Force of Codon Usage Bias in the Hepatitis A Virus Capsid [PDF]
, 2010 Hepatitis A virus (HAV), the prototype of genus Hepatovirus, has several unique biological characteristics that distinguish it from other members of the Picornaviridae family.
Pintó Solé, Rosa María +14 more
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UMCCTS Newsletter, August 2023 [PDF]
, 2023 This is the August 2023 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through ...
UMass Center for Clinical and Translational Science
core +1 more source
Nature Communications, 2020 Both agonism and antagonism of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lead to weight loss in combination with glucagon-like peptide-1 receptor agonists in preclinical models.
Elizabeth A. Killion +12 more
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Recombination, meiotic expression and human codon usage
eLife, 2017 Synonymous codon usage (SCU) varies widely among human genes. In particular, genes involved in different functional categories display a distinct codon usage, which was interpreted as evidence that SCU is adaptively constrained to optimize translation ...
Fanny Pouyet +3 more
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Balanced codon usage optimizes eukaryotic translational efficiency. [PDF]
PLoS Genetics, 2012 Cellular efficiency in protein translation is an important fitness determinant in rapidly growing organisms. It is widely believed that synonymous codons are translated with unequal speeds and that translational efficiency is maximized by the exclusive ...
Wenfeng Qian +4 more
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