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Solving the riddle of codon usage preferences: a test for translational selection [PDF]
, 1998 Translational selection is responsible for the unequal usage of synonymous codons in protein coding genes in a wide variety of organisms. It is one of the most subtle and pervasive forces of molecular evolution, yet, establishing the underlying causes ...
A Kaminskii +17 more
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The Translator’s Adaptation and Selection in the Approach to Translation as Adaptation and Selection
Pacific International Journal, 2023 San Zi Jing, with short form, pleasing rhythm and profound significance, is a well-known and representative classic among ancient enlightenment children’s books in traditional Chinese society. The core of Translation as Adaptation and Selection is the translator’s adaptation to the translational eco-environment of the original text and the ...
openaire +1 more source
Frontiers in Cellular and Infection Microbiology, 2018 Live attenuated vaccines are widely used to protect humans or animals from pathogen infections. We have previously developed a chicken embryo-attenuated Duck Hepatitis A Virus genotype 1 (DHAV-1) vaccine (CH60 strain).
Xumin Ou +48 more
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eIF1 modulates the recognition of suboptimal translation initiation sites and steers gene expression via uORFs [PDF]
, 2017 Alternative translation initiation mechanisms such as leaky scanning and reinitiation potentiate the polycistronic nature of human transcripts. By allowing for reprogrammed translation, these mechanisms can mediate biological responses to stimuli.
Fijalkowska, Daria +5 more
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Analysis of factors shaping synonymous codon usage in pseudorabies virus
浙江大学学报. 农业与生命科学版, 2007 Synonymous codon usage and the main factors shaping codon usage in pseudorabies virus were reported in order to understand the architecture and evolution of pseudorabies virus.
YIN Hua-ping +3 more
doaj +1 more source
Selection of functional human antibodies from retroviral display libraries [PDF]
, 2004 Antibody library technology represents a powerful tool for the discovery and design of antibodies with high affinity and specificity for their targets.
Urban, Johannes H. +6 more
core +2 more sources
Human T cell glycosylation and implications on immune therapy for cancer [PDF]
, 2020 Glycosylation is an important post-translational modification, giving rise to a diverse and abundant repertoire of glycans on the cell surface, collectively known as the glycome.
Callewaert, Nico +3 more
core +1 more source
Nature Communications, 2020 Both agonism and antagonism of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lead to weight loss in combination with glucagon-like peptide-1 receptor agonists in preclinical models.
Elizabeth A. Killion +12 more
doaj +1 more source
Balanced codon usage optimizes eukaryotic translational efficiency. [PDF]
PLoS Genetics, 2012 Cellular efficiency in protein translation is an important fitness determinant in rapidly growing organisms. It is widely believed that synonymous codons are translated with unequal speeds and that translational efficiency is maximized by the exclusive ...
Wenfeng Qian +4 more
doaj +1 more source
Recombination, meiotic expression and human codon usage
eLife, 2017 Synonymous codon usage (SCU) varies widely among human genes. In particular, genes involved in different functional categories display a distinct codon usage, which was interpreted as evidence that SCU is adaptively constrained to optimize translation ...
Fanny Pouyet +3 more
doaj +1 more source