Results 121 to 130 of about 2,068,781 (331)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Translator’s Preface as a Genre: A Comparative Analysis of Lithuanian and English Prefaces

open access: yesDarnioji daugiakalbystė, 2018
Translations serve as a right to the international existence as they allow the national literature to reach wider audiences. Moreover, they allow readers to get acquainted with literature of other cultures.
Bikmanienė Milda
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

El milagro secreto de Emilio Renzi: Otra vuelta a la novela del porvenir

open access: yesCuadernos LIRICO, 2019
This article analyzes the effect of the publication of Los diarios de Emilio Renzi in the concept of Ricardo Piglia’s “novela del porvenir”. A partial reading of the Diarios is made next to several specific moments from Piglia’s work, in which the ...
Sergio Waisman
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

The Psychometric Properties of Falls Efficacy Scale in the Elderly Iranian Residents of Nursing Homes

open access: yesIranian Rehabilitation Journal, 2019
Objectives: The elderly residents of nursing homes experience falling at least once a year. The fear of falling influences the quality of life and causes limitations in their daily living activities.
Mahsa Fadavi-Ghaffari   +4 more
doaj  

Translation and validation of the East Asian Acculturation Measure (EAAM) among Myanmar migrants in Thailand

open access: yesBelitung Nursing Journal
Background: Acculturation provides a framework for exploring the health behaviors of ethnic minority or cultural groups. Research on the acculturation level and patterns of Myanmar migrants is crucial since there is ample evidence that acculturation ...
Htet Shwe Wah Oo   +2 more
doaj   +1 more source

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